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Jan Rosa

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Articles 28
Citations 480
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Recent Articles
1.
Iyer A, Gurumurthy A, Chu S, Kodgule R, Aguilar A, Saari T, et al.
Blood Cancer Discov . 2025 Mar; PMID: 40067173
High expression of MYC and its target genes identify germinal center B-cell diffuse large B-cell lymphomas (GCB-DLBCL) associated with poor outcomes. We used CRISPR-interference profiling of human lymphoma cell lines...
2.
Chung Y, Langdahl B, Plebanski R, Czerwinski E, Dokoupilova E, Supronik J, et al.
Bone . 2024 Dec; 192():117371. PMID: 39674388
Purpose: This study evaluated the efficacy, safety, pharmacodynamics (PD), pharmacokinetics (PK), and immunogenicity of SB16 versus reference denosumab (DEN) up to 18 months in postmenopausal osteoporosis (PMO) patients, and assessed...
3.
Tisch A, Madapoosi S, Blough S, Rosa J, Eddy S, Mariani L, et al.
Heliyon . 2024 Oct; 10(19):e38567. PMID: 39403515
Introduction: Single-cell RNA sequencing (scRNA-seq) and single-nucleus RNA sequencing (snRNA-seq) provide valuable insights into the cellular states of kidney cells. However, the annotation of cell types often requires extensive domain...
4.
Langdahl B, Chung Y, Plebanski R, Czerwinski E, Dokoupilova E, Supronik J, et al.
J Clin Endocrinol Metab . 2024 Sep; PMID: 39243386
Context: SB16 is a proposed biosimilar to reference denosumab (DEN; brand name: Prolia). Objective: This phase 3 randomized, double-blind, multicenter study evaluated the biosimilarity of SB16 to DEN in women...
5.
Rosa J
Vnitr Lek . 2023 Jul; 69(4):254-260. PMID: 37468295
Osteomalacia with characteristic histomorphometric, radiographic, laboratory and clinical features is a prominent syndrome of disturbed bone mineralisation in adulthood. From an etiological point of view, osteomalacia is usually caused by...
6.
Kroupova K, Palicka V, Rosa J
Drugs Today (Barc) . 2023 Feb; 59(3):195-204. PMID: 36847627
Osteoporosis is a chronic disease with high unmet medical need. It is characterized by low bone mass and deteriorated bone architecture, leading to increased risk of fragility fractures, with vertebral...
7.
Zelinka T, Petrak O, Rosa J, Holaj R, Strauch B, Widimsky Jr J
Kidney Blood Press Res . 2020 Mar; 45(2):275-285. PMID: 32114578
Objective: Primary aldosteronism (PA) may present at younger age and may thus complicate pregnancy. Our aim was to identify female patients in whom PA was diagnosed after pregnancy complicated with...
8.
Petrak O, Rosa J, Holaj R, Strauch B, Kratka Z, Kvasnicka J, et al.
J Clin Endocrinol Metab . 2019 Apr; 104(11):5170-5180. PMID: 31009053
Context: Impaired diurnal blood pressure (BP) variability is related to higher cardiovascular risk. Objective: To assess diurnal variability of BP and its relation to target organ damage (TOD) and catecholamine...
9.
Klimova J, Zelinka T, Rosa J, Strauch B, Haluzikova D, Haluzik M, et al.
Cancers (Basel) . 2019 Apr; 11(4). PMID: 30959789
Fibroblast growth factor 21 (FGF21) is a hepatokine with beneficial effects on metabolism. Our aim was to evaluate the relationship between the serum FGF21, and energy and glucose metabolism in...
10.
Kvasnicka J, Zelinka T, Petrak O, Rosa J, Strauch B, Kratka Z, et al.
Cancers (Basel) . 2019 Mar; 11(3). PMID: 30845735
: Pheochromocytomas (PHEO) are tumors arising from chromaffin cells from the adrenal medulla, having the ability to produce, metabolize and secrete catecholamines. The overproduction of catecholamines leads by many mechanisms...