Jan Mehnert
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Explore the profile of Jan Mehnert including associated specialties, affiliations and a list of published articles.
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41
Citations
961
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Recent Articles
1.
Schramm S, Borner-Schroder C, Reichert M, Ramschutz C, Androulakis X, Ashina M, et al.
Neurology
. 2025 Feb;
104(5):e210235.
PMID: 39928906
Background And Objectives: Migraine is a multifaceted primary headache disorder. In neuroimaging of migraine, fMRI has been used to elucidate pathophysiology or monitor treatment effects. The current literature, however, is...
2.
Mehnert J, Tinnermann A, Basedau H, May A
Sci Adv
. 2024 Mar;
10(12):eadj8213.
PMID: 38507498
The periaqueductal gray (PAG) is located in the mesencephalon in the upper brainstem and, as part of the descending pain modulation, is considered a crucial structure for pain control. Its...
3.
Basedau H, May A, Mehnert J
Eur J Pain
. 2023 Nov;
28(5):719-728.
PMID: 38013614
Introduction: The somatotopic organization of the human cerebellum processes somato-motoric input. Its role during pain perception for nociceptive input remains ambiguous. A standardized experimental trigeminal nociceptive input in functional imaging...
4.
Mehnert J, Fischer-Schulte L, May A
Headache
. 2023 Jul;
63(8):1040-1044.
PMID: 37449553
Objectives/background: As cortical spreading depolarization (CSD) has been suggested to be the cause of migraine aura and as CSD can activate trigeminal nociceptive neurons in animals, it has been suggested...
5.
Mehnert J, Basedau H, Sturm L, Nielsen T, Jensen R, May A
Cephalalgia
. 2023 May;
43(5):3331024231174862.
PMID: 37203351
Background: The human in-vivo functional somatotopy of the three branches of the trigeminal (V1, V2, V3) and greater occipital nerve in brainstem and also in thalamus and insula is still...
6.
Basedau H, Peng K, May A, Mehnert J
Front Neurosci
. 2022 Jun;
16:802239.
PMID: 35651631
The interest in exploring trigeminal pain processing has grown in recent years, mainly due to various pathologies (such as migraine) related to this system. However, research efforts have mainly focused...
7.
Basedau H, Sturm L, Mehnert J, Peng K, Schellong M, May A
Elife
. 2022 May;
11.
PMID: 35604755
Background: Monoclonal antibodies (mAbs) against calcitonin gene-related peptides (CGRP) are novel treatments for migraine prevention. Based on a previous functional imaging study which investigated the CGRP receptor mAb (erenumab), we...
8.
Klempir O, Krupicka R, Mehnert J, Cejka V, Polakova K, Brozova H, et al.
J Appl Biomed
. 2021 Dec;
17(3):157-166.
PMID: 34907697
Exploration of motor cortex activity is essential to understanding the pathophysiology in Parkinson's Disease (PD), but only simple motor tasks can be investigated using a fMRI or PET. We aim...
9.
Moller M, Schroder C, Iwersen-Bergmann S, Mehnert J, May A
Cephalalgia
. 2021 Aug;
42(1):37-43.
PMID: 34407645
Background: Unlike other non-steroidal anti-inflammatory drugs, indomethacin has been shown to be highly effective in two forms of trigeminal autonomic cephalalgias, hemicrania continua and paroxysmal hemicrania and in some forms...
10.
Basedau H, Nielsen T, Asmussen K, Gloss K, Mehnert J, Jensen R, et al.
Pain
. 2021 Jul;
163(4):729-734.
PMID: 34326294
The existence of a trigeminocervical complex has been suggested based on animal data, but only indirect evidence exists in humans. We investigated the functional relationship between the trigeminal and the...