Jan M Keppel Hesselink
Overview
Explore the profile of Jan M Keppel Hesselink including associated specialties, affiliations and a list of published articles.
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45
Citations
391
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Recent Articles
1.
Kopsky D, van Eijk R, Warendorf J, Keppel Hesselink J, Notermans N, Vrancken A
Trials
. 2022 Oct;
23(1):888.
PMID: 36273216
Background: Patients with chronic idiopathic axonal polyneuropathy (CIAP) can have neuropathic pain that significantly impacts quality of life. Oral neuropathic pain medication often has insufficient pain relief and side effects....
2.
Kopsky D, Keppel Hesselink J, Russell A, Vrancken A
J Pain Res
. 2022 Feb;
15:377-383.
PMID: 35173477
Purpose: Topical phenytoin can act as an analgesic in chronic pain, but it is unclear if topical phenytoin gives rise to systemic side effects. Therefore, the aim of this study...
3.
Kopsky D, Vrancken A, Keppel Hesselink J, van Eijk R, Notermans N
J Pain Res
. 2020 May;
13:877-882.
PMID: 32431536
Purpose: Topical analgesics are an upcoming treatment option for neuropathic pain. In this observational study, we performed a double-blind placebo-controlled response test (DOBRET) in patients with polyneuropathy to determine the...
4.
Russell A, Kopsky D, Keppel Hesselink J
J Pain Palliat Care Pharmacother
. 2020 Mar;
34(2):99-105.
PMID: 32118498
Chronic sciatic pain is difficult to treat. Patients often suffer from considerable pain and are severely hampered in their everyday activities. Most pharmacologic analgesic treatments have disappointing effects, and often...
5.
Keppel Hesselink J
J Pain Res
. 2020 Feb;
13:123-130.
PMID: 32021401
Ceruletide (CRL) is a decapeptide, originating from the skin of a tropical frog, and is many times more potent that cholecystokinin (CCK) in a number of assays. The compound was...
6.
Liebregts R, Keppel Hesselink J, Kopsky D
Pain Med
. 2019 Apr;
20(10):2077-2079.
PMID: 30986300
No abstract available.
7.
Keppel Hesselink J, Kopsky D, Bhaskar A
J Pain Res
. 2019 Jan;
12:345-352.
PMID: 30679922
At our center in the Netherlands, patients, who very often are treatment resistant to the analgesics recommended in the guidelines, suffering from symmetrical peripheral neuropathic pain are treated exclusively. We...
8.
Keppel Hesselink J, Schatman M
J Pain Res
. 2018 Dec;
11:2991-2995.
PMID: 30538538
The repurposing of old drugs for new indications is becoming more accepted as a cost-efficient solution for complicated health problems. However, older drugs are often forgotten when they are not...
9.
Keppel Hesselink J, Schatman M
J Pain Res
. 2018 Dec;
11:2847-2851.
PMID: 30519086
No abstract available.
10.
Kopsky D, Keppel Hesselink J
Pharmaceuticals (Basel)
. 2018 Nov;
11(4).
PMID: 30424471
Background: Phenytoin cream applied topically has been explored in neuropathic pain conditions. In several case series, phenytoin 5% and 10% cream could reduce pain in a clinically relevant way with...