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Jan Konrad Siwicki

Explore the profile of Jan Konrad Siwicki including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 150
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Recent Articles
1.
Zajdel M, Szafron L, Paziewska A, Rymkiewicz G, Dabrowska M, Bystydzienski Z, et al.
Int J Mol Sci . 2025 Jan; 26(1. PMID: 39796140
High-grade B-cell lymphoma with 11q aberration (HGBCL-11q) is a rare germi-nal centre lymphoma characterised by a typical gain/loss pattern on chromo-some 11q but without MYC translocation. It shares some features...
2.
Kulinczak M, Sromek M, Panek G, Zakrzewska K, Lotocka R, Szafron L, et al.
Genes (Basel) . 2022 Sep; 13(9). PMID: 36140779
Molecular alterations in tumor-adjacent tissues have recently been recognized in some types of cancer. This phenomenon has not been studied in endometrial cancer. We aimed to analyze the expression of...
3.
Sromek M, Rymkiewicz G, Paziewska A, Szafron L, Kulecka M, Zajdel M, et al.
Biomolecules . 2021 Sep; 11(9). PMID: 34572608
The diagnosis of primary central nervous system (CNS) lymphoma, which is predominantly of the diffuse large B-cell lymphoma type (CNS DLBCL), is challenging. MicroRNAs (miRs) are gene expression-regulating non-coding RNAs...
4.
Zajdel M, Rymkiewicz G, Sromek M, Cieslikowska M, Swoboda P, Kulinczak M, et al.
Cancers (Basel) . 2019 Nov; 11(11). PMID: 31731456
Primary central nervous system lymphoma (PCNSL) is a rare, highly aggressive, extranodal form of non-Hodgkin lymphoma, predominantly diagnosed as primary diffuse large B-cell lymphoma of the central nervous system (CNS...
5.
Rymkiewicz G, Grygalewicz B, Chechlinska M, Blachnio K, Bystydzienski Z, Romejko-Jarosinska J, et al.
Mod Pathol . 2018 Jan; 31(5):732-743. PMID: 29327714
We previously described a subset of MYC translocation-negative aggressive B-cell lymphomas resembling Burkitt lymphoma, characterized by proximal gains and distal losses in chromosome 11. In the 2016 WHO classification, these...
6.
Sromek M, Glogowski M, Chechlinska M, Kulinczak M, Szafron L, Zakrzewska K, et al.
Cell Oncol (Dordr) . 2017 Jun; 40(5):529-536. PMID: 28634901
Purpose: The majority of non-small cell lung cancer (NSCLC) patients presents with an advanced-stage disease and, consequently, exhibits a poor overall survival rate. We aimed to assess changes in plasma...
7.
Swiercz A, Chechlinska M, Kupryjanczyk J, Dansonka-Mieszkowska A, Rembiszewska A, Goryca K, et al.
Anticancer Res . 2015 Apr; 35(4):2423-9. PMID: 25862909
Background/aim: miR-7 has recently been linked to cancer. Some miR-7 targets, including B-cell lymphoma 2 (BCL2) and epidermal growth factor receptor (EGFR), are involved in ovarian cancer (OC) pathogenesis. The...
8.
Zajdel M, Rymkiewicz G, Chechlinska M, Blachnio K, Pienkowska-Grela B, Grygalewicz B, et al.
Tumour Biol . 2015 Feb; 36(7):5377-88. PMID: 25677902
Fast and reliable differential diagnosis of Burkitt lymphoma (BL) vs. diffuse large B cell lymphoma (DLBCL) is of major importance for therapeutic decisions and patient outcome. Aggressive B cell non-Hodgkin...
9.
Degerman S, Landfors M, Siwicki J, Revie J, Borssen M, Evelonn E, et al.
Neoplasia . 2014 Jul; 16(7):606-15. PMID: 25065939
We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same...
10.
Degerman S, Siwicki J, Osterman P, Lafferty-Whyte K, Keith W, Roos G
Aging Cell . 2010 Jan; 9(2):220-35. PMID: 20089118
Our knowledge on immortalization and telomere biology is mainly based on genetically manipulated cells analyzed before and many population doublings post growth crisis. The general view is that growth crisis...