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Jan H Bergmann

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Recent Articles
1.
Sieber P, Schafer A, Lieberherr R, Caimi S, Luthi U, Ryge J, et al.
JCI Insight . 2022 Dec; 8(3). PMID: 36520540
In the progression phase of idiopathic pulmonary fibrosis (IPF), the normal alveolar structure of the lung is lost and replaced by remodeled fibrotic tissue and by bronchiolized cystic airspaces. Although...
2.
Li M, Amaral P, Cheung P, Bergmann J, Kinoshita M, Kalkan T, et al.
Elife . 2017 Aug; 6. PMID: 28820723
Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated for lineage specification. This transition is coordinated at multiple levels....
3.
Martins N, Bergmann J, Shono N, Kimura H, Larionov V, Masumoto H, et al.
Mol Biol Cell . 2015 Nov; 27(1):177-96. PMID: 26564795
Centromeres are characterized by the centromere-specific H3 variant CENP-A, which is embedded in chromatin with a pattern characteristic of active transcription that is required for centromere identity. It is unclear...
4.
Bergmann J, Li J, Eckersley-Maslin M, Rigo F, Freier S, Spector D
Genome Res . 2015 Jun; 25(9):1336-46. PMID: 26048247
Long noncoding (lnc)RNAs have recently emerged as key regulators of gene expression. Here, we performed high-depth poly(A)(+) RNA sequencing across multiple clonal populations of mouse embryonic stem cells (ESCs) and...
5.
Bell R, Long X, Lin M, Bergmann J, Nanda V, Cowan S, et al.
Arterioscler Thromb Vasc Biol . 2014 Mar; 34(6):1249-59. PMID: 24578380
Objective: Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA genes with functions related primarily to transcriptional and post-transcriptional control of gene expression. There is a paucity of...
6.
Eckersley-Maslin M, Thybert D, Bergmann J, Marioni J, Flicek P, Spector D
Dev Cell . 2014 Mar; 28(4):351-65. PMID: 24576421
Random autosomal monoallelic gene expression refers to the transcription of a gene from one of two homologous alleles. We assessed the dynamics of monoallelic expression during development through an allele-specific...
7.
Bergmann J, Spector D
Curr Opin Cell Biol . 2014 Feb; 26:10-8. PMID: 24529241
Long non-coding (lnc)RNAs are emerging key factors in the regulation of various cellular processes. In the nucleus, these include the organization of nuclear sub-structures, the alteration of chromatin state, and...
8.
Eckersley-Maslin M, Bergmann J, Lazar Z, Spector D
Nucleus . 2013 Jan; 4(1):53-60. PMID: 23324457
The pluripotent nature of embryonic stem cells (ESC) is associated with a dynamic open chromatin state and an irregular nuclear shape. It has been postulated that the absence of Lamin...
9.
Bergmann J, Martins N, Larionov V, Masumoto H, Earnshaw W
Chromosome Res . 2012 Jul; 20(5):505-19. PMID: 22825423
The centromere is a specialized chromosomal region that serves as the assembly site of the kinetochore. At the centromere, CENP-A nucleosomes form part of a chromatin landscape termed centrochromatin. This...
10.
Ohzeki J, Bergmann J, Kouprina N, Noskov V, Nakano M, Kimura H, et al.
EMBO J . 2012 Apr; 31(10):2391-402. PMID: 22473132
The kinetochore is responsible for accurate chromosome segregation. However, the mechanism by which kinetochores assemble and are maintained remains unclear. Here we report that de novo CENP-A assembly and kinetochore...