Jan Gustav Ruppert
Overview
Explore the profile of Jan Gustav Ruppert including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
42
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0
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Recent Articles
1.
Holm J, Ruppert J, Ramsden S
Pharmaceut Med
. 2022 Jan;
36(1):33-46.
PMID: 35099785
Introduction: The European Risk Management Plan (EU-RMP) is a proactive planning tool for identification, characterisation and management of important risks and missing information throughout the lifecycle of a medicinal product....
2.
Schneikert J, Ruppert J, Behrens J, Wenzel E
PLoS One
. 2014 Apr;
9(4):e94413.
PMID: 24722208
Wnt signalling is prevented by the proteosomal degradation of β-catenin, which occurs in a destruction complex containing adenomatous polyposis coli (APC), APC-like (APCL), Axin and Axin2. Truncating mutations of the...
3.
Wu M, Li C, Ruppert J, Chang C
Biochem Biophys Res Commun
. 2013 Nov;
441(3):618-23.
PMID: 24183726
Defective human leukocyte antigen (HLA) class I expression in malignant cells facilitates their escape from destruction by CD8(+) cytotoxic T lymphocytes. In this study, a post-translational mechanism of HLA class...
4.
Schneikert J, Vijaya Chandra S, Ruppert J, Ray S, Wenzel E, Behrens J
PLoS One
. 2013 Jul;
8(7):e68072.
PMID: 23840886
Truncating mutations affect the adenomatous polyposis coli (APC) gene in most cases of colon cancer, resulting in the stabilization of β-catenin and uncontrolled cell proliferation. We show here that colon...