Jan Beckendorf
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Explore the profile of Jan Beckendorf including associated specialties, affiliations and a list of published articles.
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11
Citations
177
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Recent Articles
1.
Haney A, Siry D, Hoerbrand I, Ehlermann P, Beckendorf J
Eur Heart J Case Rep
. 2024 May;
8(5):ytae204.
PMID: 38707531
Background: One of the main causes of myocardial infarction during pregnancy is spontaneous coronary artery dissection. This is ascribed to hormonal changes during pregnancy leading to a weakening of the...
2.
Tager T, Rossmann P, Frey N, Estler B, Mack M, Schlegel P, et al.
Cardiology
. 2023 Jul;
148(6):485-496.
PMID: 37517385
Introduction: The long-term evolution of clinical, echocardiographic, and laboratory parameters of cardiac function in patients with chronic heart failure (HF) with either reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular...
3.
Frohlich H, Frey N, Estler B, Mack M, Schlegel P, Beckendorf J, et al.
Am J Cardiovasc Drugs
. 2022 Sep;
22(6):695-704.
PMID: 36136241
Background: Sacubitril/valsartan (S/V) improves outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Data about the immediate, short-, and intermediate-term hemodynamic effects of S/V are limited. Methods: In...
4.
Werhahn S, Kreusser J, Hagenmuller M, Beckendorf J, Diemert N, Hoffmann S, et al.
PLoS One
. 2021 Jun;
16(6):e0248933.
PMID: 34138844
On the one hand, sustained β-adrenergic stress is a hallmark of heart failure (HF) and exerts maladaptive cardiac remodelling. On the other hand, acute β-adrenergic stimulation maintains cardiac function under...
5.
Sawall S, Beckendorf J, Amato C, Maier J, Backs J, Velde G, et al.
Sci Rep
. 2020 Oct;
10(1):16866.
PMID: 33033290
Coronary computed tomography angiography is an established technique in clinical practice and a valuable tool in the diagnosis of coronary artery disease in humans. Imaging of coronaries in preclinical research,...
6.
Kreusser M, Tschierschke R, Beckendorf J, Baxmann T, Frankenstein L, Dosch A, et al.
ESC Heart Fail
. 2018 Jul;
5(6):1108-1117.
PMID: 29984916
Aim: With an increasing prevalence of heart failure (HF), more patients with advanced disease have to be treated in cardiology units by sophisticated medical and interventional strategies. We therefore developed...
7.
Beckendorf J, van den Hoogenhof M, Backs J
Basic Res Cardiol
. 2018 Jun;
113(4):29.
PMID: 29905892
In the cardiomyocyte, CaMKII has been identified as a nodal influencer of excitation-contraction and also excitation-transcription coupling. Its activity can be regulated in response to changes in intracellular calcium content...
8.
Sawall S, Franke D, Kirchherr A, Beckendorf J, Kuntz J, Maier J, et al.
Contrast Media Mol Imaging
. 2017 Nov;
2017:2617047.
PMID: 29114173
We herein developed a micro-CT method using the innovative contrast agent ExiTron™ MyoC 8000 to longitudinally monitor cardiac processes in small animals. Experiments were performed on healthy mice and mice...
9.
Helmschrott M, Beckendorf J, Akyol C, Ruhparwar A, Schmack B, Erbel C, et al.
Drug Des Devel Ther
. 2014 Sep;
8:1307-14.
PMID: 25246772
Background: The use of tacrolimus (TAC) in patients after heart transplantation (HTX) has increased over the last few years. Aim: In this retrospective study, we evaluated the effects of a...
10.
Weinreuter M, Kreusser M, Beckendorf J, Schreiter F, Leuschner F, Lehmann L, et al.
EMBO Mol Med
. 2014 Sep;
6(10):1231-45.
PMID: 25193973
CaMKII was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. Here, we investigated the roles of different CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury by the...