Jan Aaseth
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Explore the profile of Jan Aaseth including associated specialties, affiliations and a list of published articles.
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129
Citations
3334
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Recent Articles
1.
Bjorklund G, Semenova Y, Hangan T, Pen J, Aaseth J, Peana M
Curr Med Chem
. 2024 Apr;
31(12):1428-1440.
PMID: 38572614
Iron (Fe) is a necessary trace element in numerous pathways of human metabolism. Therefore, Fe deficiency is capable of causing multiple health problems. Apart from the well-known microcytic anemia, lack...
2.
Opstad T, Alexander J, Aaseth J, Larsson A, Seljeflot I, Alehagen U
Antioxidants (Basel)
. 2023 Mar;
12(3).
PMID: 36979007
: Selenium and coenzyme Q (SeQ) possess antioxidant and anti-inflammatory properties, potentially mediated via Sirtuin1 (SIRT1). We aimed to investigate the influence of a SeQ intervention on SIRT1 concentration, with...
3.
Skalny A, Aschner M, Sekacheva M, Santamaria A, Barbosa F, Ferrer B, et al.
Food Chem Toxicol
. 2022 Apr;
164:113001.
PMID: 35447290
The present study aims to review epidemiological and experimental toxicology studies published over the last two decades linking mercury (Hg) exposure and carcinogenesis, with a special emphasis on the potential...
4.
Alehagen U, Johansson P, Svensson E, Aaseth J, Alexander J
Eur J Nutr
. 2022 Apr;
61(6):3135-3148.
PMID: 35381849
Purpose: Selenium and coenzyme Q10 have synergistic antioxidant functions. In a four-year supplemental trial in elderly Swedes with a low selenium status, we found improved cardiac function, less cardiac wall...
5.
Aaseth J, Javorac D, Djordjevic A, Bulat Z, Skalny A, Zaitseva I, et al.
Toxics
. 2022 Feb;
10(2).
PMID: 35202251
Persistent organic pollutants (POPs) are considered as potential obesogens that may affect adipose tissue development and functioning, thus promoting obesity. However, various POPs may have different mechanisms of action. The...
6.
Alehagen U, Aaseth J, Larsson A, Alexander J
Cells
. 2022 Feb;
11(3).
PMID: 35159318
There is a reduced intake of selenium in many countries due to low levels of selenium in the soil. This results in an increased cardiovascular risk. Fibroblast growth factor 23...
7.
Skalny A, Aschner M, Lei X, Gritsenko V, Santamaria A, Alekseenko S, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884881
The objective of the present study was to review the existing data on the association between Zn status and characteristics of gut microbiota in various organisms and the potential role...
8.
Alehagen U, Opstad T, Alexander J, Larsson A, Aaseth J
Biomolecules
. 2021 Oct;
11(10).
PMID: 34680111
Selenium (Se) is an essential dietary trace element that plays an important role in the prevention of inflammation, cardiovascular diseases, infections, and cancer. Selenoproteins contain selenocysteine in the active center...
9.
Aaseth J, Skalny A, Roos P, Alexander J, Aschner M, Tinkov A
Int J Mol Sci
. 2021 Sep;
22(17).
PMID: 34502369
The aim of the present review is to discuss traditional hypotheses on the etiopathogenesis of Alzheimer's disease (AD), as well as the role of metabolic-syndrome-related mechanisms in AD development with...
10.
Aaseth J, Alexander J, Alehagen U, Tinkov A, Skalny A, Larsson A, et al.
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439746
The aging process in the kidneys has been well studied. It is known that the glomerular filtration rate (GFR) declines with age in subjects older than 50-60 years. However, there...