Jan A Rath
Overview
Explore the profile of Jan A Rath including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
79
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0
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Recent Articles
1.
Jaccard A, Wyss T, Maldonado-Perez N, Rath J, Bevilacqua A, Peng J, et al.
Nature
. 2023 Sep;
621(7980):849-856.
PMID: 37730993
Protective immunity against pathogens or cancer is mediated by the activation and clonal expansion of antigen-specific naive T cells into effector T cells. To sustain their rapid proliferation and effector...
2.
Rath J, Bajwa G, Carreres B, Hoyer E, Gruber I, Martinez-Paniagua M, et al.
Sci Adv
. 2020 Sep;
6(27):eaaz7809.
PMID: 32923584
Transgenic coexpression of a class I-restricted tumor antigen-specific T cell receptor (TCR) and CD8αβ (TCR8) redirects antigen specificity of CD4 T cells. Reinforcement of biophysical properties and early TCR signaling...
3.
Rath J, Arber C
Cells
. 2020 Jun;
9(6).
PMID: 32570906
T cell receptor (TCR)-based adoptive T cell therapies (ACT) hold great promise for the treatment of cancer, as TCRs can cover a broad range of target antigens. Here we summarize...