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Jan-Patrick Fischer

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Articles 6
Citations 39
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Recent Articles
1.
Julke E, Fischer J, Els-Heindl S, Bierer D, Flamme I, Kobberling J, et al.
J Pept Sci . 2023 Jul; 29(12):e3530. PMID: 37423610
The peptide hormone adrenomedullin (ADM) consists of 52 amino acids with a disulfide bond and an amidated C-terminus. Due to the vasodilatory and cardioprotective effects, the agonistic activity of the...
2.
Reif A, Lam K, Weidler S, Lott M, Boos I, Lokau J, et al.
Angew Chem Int Ed Engl . 2021 Mar; 60(24):13380-13387. PMID: 33756033
A library of glycoforms of human interleukin 6 (IL-6) comprising complex and mannosidic N-glycans was generated by semisynthesis. The three segments were connected by sequential native chemical ligation followed by...
3.
Fischer J, Els-Heindl S, Beck-Sickinger A
Peptides . 2020 Jun; 131:170347. PMID: 32569606
The peptide hormone adrenomedullin (ADM) consists of 52 amino acids and plays a pivotal role in the regulation of many physiological processes, particularly those of the cardiovascular and lymphatic system....
4.
Fischer J, Schonauer R, Els-Heindl S, Bierer D, Koebberling J, Riedl B, et al.
J Pept Sci . 2019 Jan; 25(3):e3147. PMID: 30680847
Adrenomedullin (ADM) is a vasoactive peptide hormone of 52 amino acids and belongs to the calcitonin peptide superfamily. Its vasodilative effects are mediated by the interaction with the calcitonin receptor-like...
5.
Fischer J, Els-Heindl S, Schonauer R, Bierer D, Kobberling J, Riedl B, et al.
ChemMedChem . 2018 Jul; 13(17):1797-1805. PMID: 29979487
Adrenomedullin (ADM) is a peptide hormone of the calcitonin gene-related peptide (CGRP) family. It is involved in the regulation of cardiovascular processes such as angiogenesis, vasodilation, and the reduction of...
6.
Schonauer R, Els-Heindl S, Fischer J, Kobberling J, Riedl B, Beck-Sickinger A
J Med Chem . 2016 May; 59(12):5695-705. PMID: 27166982
The 52 amino acid peptide hormone adrenomedullin (ADM) plays a major role in the development and regulation of the cardiovascular and lymphatic system and has therefore gained significant interest for...