James Witter
Overview
Explore the profile of James Witter including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
4303
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0
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Recent Articles
1.
Gewandter J, Dworkin R, Turk D, Devine E, Hewitt D, Jensen M, et al.
J Pain
. 2019 Dec;
21(9-10):931-942.
PMID: 31843583
The estimated probability of progressing from phase 3 analgesic clinical trials to regulatory approval is approximately 57%, suggesting that a considerable number of treatments with phase 2 trial results deemed...
2.
Ahmed S, Ware P, Gardner W, Witter J, Bingham 3rd C, Kairy D, et al.
J Clin Epidemiol
. 2017 Apr;
89:160-167.
PMID: 28433675
Background: Given that the goal of health care systems is to improve and maintain the health of the populations they serve, the indicators of performance must include outcomes that are...
3.
Bartlett S, Witter J, Cella D, Ahmed S
J Clin Epidemiol
. 2017 Apr;
89:148-153.
PMID: 28433674
Background: Patient-reported outcome (PRO) data are beneficial to a range of stakeholders including patients, clinicians, researchers, national funding and regulatory agencies, health system administrators, and policymakers. Objective: Because stakeholders represent...
4.
Smith S, Dworkin R, Turk D, Baron R, Polydefkis M, Tracey I, et al.
J Pain
. 2017 Mar;
18(7):757-777.
PMID: 28254585
Perspective: The applicability of sensory testing, skin biopsy, and brain imaging as diagnostic, prognostic, predictive, and pharmacodynamic biomarkers for use in analgesic treatment trials is considered. Evidence in support of...
5.
Taylor A, Phillips K, Patel K, Turk D, Dworkin R, Beaton D, et al.
Pain
. 2016 Apr;
157(9):1836-1850.
PMID: 27058676
Although pain reduction is commonly the primary outcome in chronic pain clinical trials, physical functioning is also important. A challenge in designing chronic pain trials to determine efficacy and effectiveness...
6.
Fries J, Witter J, Rose M, Cella D, Khanna D, Morgan-DeWitt E
J Rheumatol
. 2013 Nov;
41(1):153-8.
PMID: 24241485
Objective: Patient-reported outcome (PRO) questionnaires record health information directly from research participants because observers may not accurately represent the patient perspective. Patient-reported Outcomes Measurement Information System (PROMIS) is a US...
7.
Bruehl S, Apkarian A, Ballantyne J, Berger A, Borsook D, Chen W, et al.
J Pain
. 2013 Feb;
14(2):103-13.
PMID: 23374939
Unlabelled: Use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. There is currently no well-validated...
8.
Dworkin R, Turk D, Peirce-Sandner S, Burke L, Farrar J, Gilron I, et al.
Pain
. 2012 Apr;
153(6):1148-1158.
PMID: 22494920
A number of pharmacologic treatments examined in recent randomized clinical trials (RCTs) have failed to show statistically significant superiority to placebo in conditions in which their efficacy had previously been...
9.
Reid M, Bennett D, Chen W, Eldadah B, Farrar J, Ferrell B, et al.
Pain Med
. 2011 Aug;
12(9):1336-57.
PMID: 21834914
Objective: There has been a growing recognition of the need for better pharmacologic management of chronic pain among older adults. To address this need, the National Institutes of Health Pain...
10.
Dworkin R, Turk D, Peirce-Sandner S, Baron R, Bellamy N, Burke L, et al.
Pain
. 2010 Mar;
149(2):177-193.
PMID: 20207481
There has been an increase in the number of chronic pain clinical trials in which the treatments being evaluated did not differ significantly from placebo in the primary efficacy analyses...