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James W Wheless

Explore the profile of James W Wheless including associated specialties, affiliations and a list of published articles. Areas
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Articles 171
Citations 2893
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Recent Articles
1.
Wheless J, Becker D, Benbadis S, Puri V, Datta P, Clarke D, et al.
Neuropsychiatr Dis Treat . 2024 Nov; 20:2255-2265. PMID: 39600969
Some patients with epilepsy continue to have seizures despite daily treatment with antiseizure medications. This includes seizure clusters (also known as acute repetitive seizures), which are an increase in seizure...
2.
Sage E, Choudhri A, Lee-Diaz J, Bissler J, Wheless J
Seizure . 2024 Nov; 123:148-151. PMID: 39571475
Introduction: Individuals with tuberous sclerosis complex (TSC) often present with refractory epilepsy and may be undergoing treatment with vagus nerve stimulation (VNS) to control seizures. Surveillance magnetic resonance imaging (MRI)...
3.
Wheless J, Raskin J, Fine A, Knupp K, Schreiber J, Ostendorf A, et al.
Seizure . 2024 Nov; 123:97-103. PMID: 39536380
Purpose: To provide consensus-based recommendations for use of vagus nerve stimulation (VNS) therapy in the management of pediatric epilepsy. Methods: Delphi methodology with two rounds of online survey was used...
4.
Detyniecki K, Brunnert M, Campos R, Dimova S, Wheless J
Epilepsy Behav . 2024 Nov; 148:109483. PMID: 39491945
Objective: To characterize the time to return to full baseline functionality (RTFBF) in seizure cluster episodes (SCEs) treated with one or two midazolam nasal spray (MDZ-NS/Nayzilam®) doses over the course...
5.
Wheless J, Rho J
Epilepsia . 2024 Nov; 66(1):33-46. PMID: 39487852
Cholesterol is a critical molecule in the central nervous system, and imbalances in the synthesis and metabolism of brain cholesterol can result in a range of pathologies, including those related...
6.
Woods M, Phelps S, Christensen M, Meibohm B, Wheless J
J Pediatr Pharmacol Ther . 2024 Oct; 29(5):514-524. PMID: 39411416
Objective: To evaluate age, adjunctive antiseizure medication (ASM), and specific ASMs on lacosamide (LCM) weight normalized dose-to-concentration ratio (DCR) and US Food and Drug Administration (FDA) dosing guidelines in pediatric...
7.
Wheless J, Richardson B, Rubinos C, Faught E, Vuong M
Neurol Clin Pract . 2024 Oct; 15(1):e200362. PMID: 39399555
Purpose Of Review: Dysphagia, or difficulty swallowing, affects several individuals globally and can contribute to a reduced quality of life and partial medication adherence, especially in patients with epilepsy. There...
8.
Varner J, Rezaie R, Noorizadeh N, Boop F, Fulton S, Klimo P, et al.
Epilepsy Res . 2024 Aug; 206:107426. PMID: 39128278
Responsive neurostimulation (RNS) is a treatment option for patients with refractory epilepsy when surgical resection is not possible due to overlap of the irritative zone and eloquent cortex. Presurgical evaluations...
9.
Liow K, Wheless J, Cook D, Rabinowicz A, Carrazana E
Front Neurol . 2024 Jun; 15:1335421. PMID: 38854958
Introduction: Neurologic circadian influences, including sleep/wake transitions, processes (e.g., hormonal variation), and behavioral patterns (e.g., consumption of food and oral medications), may affect seizure patterns. Specific circadian patterns of seizures...
10.
Noorizadeh N, Rezaie R, Varner J, Wheless J, Fulton S, Mudigoudar B, et al.
Brain Sci . 2024 Apr; 14(4). PMID: 38671988
Determination of language hemispheric dominance (HD) in patients undergoing evaluation for epilepsy surgery has traditionally relied on the sodium amobarbital (Wada) test. The emergence of non-invasive methods for determining language...