James W Foley
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Explore the profile of James W Foley including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
295
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Recent Articles
1.
Ren X, Wang C, Wu X, Rong M, Huang R, Liang Q, et al.
J Am Chem Soc
. 2024 Feb;
146(10):6566-6579.
PMID: 38422385
Superior photostability, minimal phototoxicity, red-shifted absorption/emission wavelengths, high brightness, and an enlarged Stokes shift are essential characteristics of top-tier organic fluorophores, particularly for long-lasting super-resolution imaging in live cells (e.g.,...
2.
Yue X, Wang B, Lan M, Fan J, Song X, Foley J
Chem Commun (Camb)
. 2023 Mar;
59(31):4676-4679.
PMID: 36995030
AX11890, an inhibitor of overexpressed enzyme, KIAA1363, in some breast cancers, was conjugated with a benzo[]phenothiazinium photosensitizer to develop a tumor micro-environment-responsive photosensitizer NBS-L-AX. In normal cells, the special geometry...
3.
Li M, Shao Y, Kim J, Pu Z, Zhao X, Huang H, et al.
J Am Chem Soc
. 2020 Feb;
142(11):5380-5388.
PMID: 32105455
Tumor hypoxia has proven to be the major bottleneck of photodynamic therapy (PDT) to clinical transformation. Different from traditional O delivery approaches, here we describe an innovative binary photodynamic O-economizer...
4.
Li M, Xiong T, Du J, Tian R, Xiao M, Guo L, et al.
J Am Chem Soc
. 2019 Jan;
141(6):2695-2702.
PMID: 30652866
Strong oxygen dependence, poor tumor targeting, and limited treatment depth have been considered as the "Achilles' heels" facing the clinical usage of photodynamic therapy (PDT). Different from common approaches, here,...
5.
Li M, Xia J, Tian R, Wang J, Fan J, Du J, et al.
J Am Chem Soc
. 2018 Oct;
140(44):14851-14859.
PMID: 30362735
Hypoxia, a quite universal feature in most solid tumors, has been considered as the "Achilles' heel" of traditional photodynamic therapy (PDT) and substantially impairs the overall therapeutic efficacy. Herein, we...
6.
Liu X, Su Y, Tian H, Yang L, Zhang H, Song X, et al.
Anal Chem
. 2017 May;
89(13):7038-7045.
PMID: 28553716
A novel lysosome-targeting ratiometric fluorescent probe (CQ-Lyso) based on the chromenoquinoline chromorphore has been developed for the selective and sensitive detection of intracellular pH in living cells. In acidic media,...
7.
Chen W, Luo H, Liu X, Foley J, Song X
Anal Chem
. 2016 Feb;
88(7):3638-46.
PMID: 26911923
Glutathione (GSH), cysteine (Cys), and homocysteine (Hcy) are small biomolecular thiols that are present in all cells and extracellular fluids of healthy mammals. It is well-known that each plays a...
8.
Verma S, Sallum U, Athar H, Rosenblum L, Foley J, Hasan T
Photochem Photobiol
. 2008 Jul;
85(1):111-8.
PMID: 18657053
5-(Ethylamino)-9-diethylaminobenzo[a]phenothiazinium chloride (EtNBS) is a photosensitizer (PS) with broad antimicrobial photodynamic activity. The objective of this study was to determine the antimicrobial photodynamic effect of side chain/end group modifications of...
9.
Song X, Kassaye D, Foley J
J Fluoresc
. 2007 Dec;
18(2):513-8.
PMID: 18058204
We have evaluated the chemical, photophysical and photostability properties of 5,9-diaminodibenzo[a,j]phenoxazinium chloride, 3, and its bis-5,9-ethylamino analogue, 4, with the goal of determining if they have characteristics that are compatible...
10.
ORiordan K, Akilov O, Chang S, Foley J, Hasan T
Photochem Photobiol Sci
. 2007 Oct;
6(10):1117-23.
PMID: 17914486
An objective was to explore the photodynamic activity of two cationic photosensitizers (PS) (benzo[a]phenothiazinium chloride and benzo[a]phenoselenazinium chloride) against Mycobacterium bovis BCG both in vitro and in a murine model...