James W Baish
Overview
Explore the profile of James W Baish including associated specialties, affiliations and a list of published articles.
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25
Citations
779
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Recent Articles
1.
Lei P, Ruscic K, Roh K, Rajotte J, OMelia M, Bouta E, et al.
Dev Cell
. 2024 Dec;
PMID: 39731913
Lymphatic muscle cells (LMCs) within the wall of collecting lymphatic vessels exhibit tonic and autonomous phasic contractions, which drive active lymph transport to maintain tissue-fluid homeostasis and support immune surveillance....
2.
Li H, Zhang J, Padera T, Baish J, Munn L
PNAS Nexus
. 2024 Jun;
3(6):pgae195.
PMID: 38827815
The lymphatic system plays a vital role in maintaining fluid balance in living tissue and serves as a pathway for the transport of antigen, immune cells, and metastatic cancer cells....
3.
Datta M, Kennedy M, Siri S, Via L, Baish J, Xu L, et al.
PLoS Comput Biol
. 2024 Feb;
20(2):e1011847.
PMID: 38335224
Physiological abnormalities in pulmonary granulomas-pathological hallmarks of tuberculosis (TB)-compromise the transport of oxygen, nutrients, and drugs. In prior studies, we demonstrated mathematically and experimentally that hypoxia and necrosis emerge in...
4.
Lei P, Ruscic K, Roh K, Rajotte J, OMelia M, Bouta E, et al.
bioRxiv
. 2023 Nov;
PMID: 38014141
Lymphatic muscle cells (LMCs) within the wall of collecting lymphatic vessels exhibit tonic and autonomous phasic contractions, which drive active lymph transport to maintain tissue-fluid homeostasis and support immune surveillance....
5.
Nikmaneshi M, Baish J, Zhou H, Padera T, Munn L
Adv Sci (Weinh)
. 2023 Nov;
10(36):e2304076.
PMID: 37949675
Effective anti-cancer immune responses require activation of one or more naïve T cells. If the correct naïve T cell encounters its cognate antigen presented by an antigen presenting cell, then...
6.
Zhou H, Menzel L, Baish J, OMelia M, Darragh L, Specht E, et al.
bioRxiv
. 2023 Oct;
PMID: 37781599
Lymphatic transport facilitates the presentation of cancer antigens in tumor-draining lymph nodes (tdLNs), leading to T cell activation and the generation of systemic antitumor immune surveillance. Surgical removal of LNs...
7.
Razavi M, Lei P, Amoozgar Z, Leartprapun N, Nadkarni S, Baish J, et al.
Res Sq
. 2023 Jul;
PMID: 37461473
Secondary lymphedema is a debilitating condition driven by impaired regeneration of lymphatic vasculature following lymphatic injury, surgical removal of lymph nodes in cancer patients or infection. However, the extent to...
8.
Li H, Wei H, Padera T, Baish J, Munn L
PNAS Nexus
. 2023 Jan;
1(5):pgac237.
PMID: 36712369
Physical forces, including mechanical stretch, fluid pressure, and shear forces alter lymphatic vessel contractions and lymph flow. Gravitational forces can affect these forces, resulting in altered lymphatic transport, but the...
9.
Baish J, Padera T, Munn L
Sci Rep
. 2022 Mar;
12(1):4890.
PMID: 35318426
Edema in the limbs can arise from pathologies such as elevated capillary pressures due to failure of venous valves, elevated capillary permeability from local inflammation, and insufficient fluid clearance by...
10.
Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy
Mpekris F, Voutouri C, Panagi M, Baish J, Jain R, Stylianopoulos T
J Control Release
. 2022 Mar;
345:190-199.
PMID: 35271911
Nanomedicine offered hope for improving the treatment of cancer but the survival benefits of the clinically approved nanomedicines are modest in many cases when compared to conventional chemotherapy. Metronomic therapy,...