James V Haist
Overview
Explore the profile of James V Haist including associated specialties, affiliations and a list of published articles.
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11
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295
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Recent Articles
1.
Gan X, Ettinger G, Huang C, Burton J, Haist J, Rajapurohitam V, et al.
Circ Heart Fail
. 2014 Mar;
7(3):491-9.
PMID: 24625365
Background: Probiotics are extensively used to promote gastrointestinal health, and emerging evidence suggests that their beneficial properties can extend beyond the local environment of the gut. Here, we determined whether...
2.
Martinez-Abundis E, Rajapurohitam V, Haist J, Gan X, Karmazyn M
PLoS One
. 2012 Aug;
7(7):e41612.
PMID: 22848545
The obesity-related 16 kDa peptide leptin is synthesized primarily in white adipocytes although its production has been reported in other tissues including the heart. There is emerging evidence that leptin...
3.
Huber J, Bentzien J, Boyer S, Burke J, De Lombaert S, Eickmeier C, et al.
J Med Chem
. 2012 Jul;
55(16):7114-40.
PMID: 22803959
Sodium-hydrogen exchanger isoform 1 (NHE1) is a ubiquitously expressed transmembrane ion channel responsible for intracellular pH regulation. During myocardial ischemia, low pH activates NHE1 and causes increased intracellular calcium levels...
4.
Guo J, Gan X, Haist J, Rajapurohitam V, Zeidan A, Faruq N, et al.
Circ Heart Fail
. 2010 Oct;
4(1):79-88.
PMID: 20971938
Background: Ginseng is a medicinal plant used widely in Asia that has gained popularity in the West during the past decade. Increasing evidence suggests a therapeutic role for ginseng in...
5.
Gan X, Gong X, Xue J, Haist J, Bai D, Karmazyn M
Cardiovasc Res
. 2009 Aug;
85(1):79-89.
PMID: 19687166
Aims: Cardiac glycosides induce cardiomyocyte hypertrophy via yet to be defined mechanisms. These hypertrophic effects are likely related to changes in intracellular signalling secondary to Na(+)-K(+) ATPase (NKA) inhibition which...
6.
Thorp D, Haist J, Leppard J, Milne K, Karmazyn M, Noble E
Am J Physiol Regul Integr Comp Physiol
. 2007 May;
293(1):R363-71.
PMID: 17507436
Acute exercise increases myocardial tolerance to ischemia-reperfusion (I-R) injury in male but not in female rat hearts, possibly due to a decreased heat shock protein 70 (Hsp70) response in the...
7.
Gan X, Rajapurohitam V, Haist J, Chidiac P, Cook M, Karmazyn M
J Pharmacol Exp Ther
. 2004 Sep;
312(1):27-34.
PMID: 15452191
Plasma adenosine levels are elevated in cardiovascular disease including hypertension and heart failure, and the nucleoside has been proposed to serve as an endogenous antimyocardial remodeling factor. We studied the...
8.
Haist J, Hirst C, Karmazyn M
Am J Physiol Heart Circ Physiol
. 2003 Feb;
284(3):H798-803.
PMID: 12578812
We compared the protective effects of ischemic preconditioning (IPC) and the Na(+)/H(+) exchanger-1 (NHE-1) inhibitor cariporide in isolated rat hearts subjected to global ischemia (45 or 90 min) and 30-min...
9.
Paroo Z, Meredith M, Locke M, Haist J, Karmazyn M, Noble E
Am J Physiol Cell Physiol
. 2002 Jul;
283(2):C404-11.
PMID: 12107049
Experiments involving chemical induction of the heat shock response in simple biological systems have generated the hypothesis that protein denaturation and consequential binding of heat shock transcription factor 1 (HSF1)...
10.
Paroo Z, Haist J, Karmazyn M, Noble E
Circ Res
. 2002 May;
90(8):911-7.
PMID: 11988493
Exercise is a physiological inducer of the cardioprotective heat shock protein, Hsp70. The putative biological events involved in signaling this response exhibit sexual dimorphism. Thus, it was hypothesized that exercise-mediated...