James T Warren
Overview
Explore the profile of James T Warren including associated specialties, affiliations and a list of published articles.
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21
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1830
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Recent Articles
1.
Hentze J, Moeller M, Jorgensen A, Bengtsson M, Bordoy A, Warren J, et al.
PLoS One
. 2013 Feb;
8(2):e55131.
PMID: 23383307
Insect steroid hormones (ecdysteroids) are important for female reproduction in many insect species and are required for the initiation and coordination of vital developmental processes. Ecdysteroids are also important for...
2.
Gibbens Y, Warren J, Gilbert L, OConnor M
Development
. 2011 May;
138(13):2693-703.
PMID: 21613324
In insects, initiation of metamorphosis requires a surge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic gland, the primary endocrine organ of juvenile larvae. Here, we show...
3.
Parisi M, Gupta V, Sturgill D, Warren J, Jallon J, Malone J, et al.
BMC Genomics
. 2010 Jun;
11:346.
PMID: 20515475
Background: Drosophila females commit tremendous resources to egg production and males produce some of the longest sperm in the animal kingdom. We know little about the coordinated regulation of gene...
4.
Warren J, OConnor M, Gilbert L
Insect Biochem Mol Biol
. 2009 Aug;
39(10):677-87.
PMID: 19699302
It has long been hypothesized that the oxidation of 7-dehydrocholesterol (7dC), made from dietary cholesterol (C), to 3-oxo-7dC (3-oxo-Delta(5,7)C) immediately precedes the unknown "Black Box" oxidations that lead to the...
5.
Elsik C, Tellam R, Worley K, Gibbs R, Muzny D, Weinstock G, et al.
Science
. 2009 Apr;
324(5926):522-8.
PMID: 19390049
To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set...
6.
Huang X, Warren J, Gilbert L
J Genet Genomics
. 2008 Jan;
35(1):1-10.
PMID: 18222403
Insect ecdysone steroid hormone regulates major developmental transitions, such as molting and metamorphosis. The production of ecdysone correlates well with the timing of these transitions. Finding out how the ecdysone...
7.
McBrayer Z, Ono H, Shimell M, Parvy J, Beckstead R, Warren J, et al.
Dev Cell
. 2007 Dec;
13(6):857-71.
PMID: 18061567
In insects, control of body size is intimately linked to nutritional quality as well as environmental and genetic cues that regulate the timing of developmental transitions. Prothoracicotropic hormone (PTTH) has...
8.
Huang X, Warren J, Buchanan J, Gilbert L, Scott M
Development
. 2007 Sep;
134(20):3733-42.
PMID: 17804599
Mutations in either of the two human Niemann-Pick type C (NPC) genes, NPC1 and NPC2, cause a fatal neurodegenerative disease associated with abnormal cholesterol accumulation in cells. npc1a, the Drosophila...
9.
Ono H, Rewitz K, Shinoda T, Itoyama K, Petryk A, Rybczynski R, et al.
Dev Biol
. 2006 Sep;
298(2):555-70.
PMID: 16949568
Ecdysteroids regulate many key developmental events in arthropods including molting and metamorphosis. Recently, members of the Drosophila Halloween group of genes, that are required for embryonic viability and cuticle deposition,...
10.
Scherer S, Muzny D, Buhay C, Chen R, Cree A, Ding Y, et al.
Nature
. 2006 Mar;
440(7082):346-51.
PMID: 16541075
Human chromosome 12 contains more than 1,400 coding genes and 487 loci that have been directly implicated in human disease. The q arm of chromosome 12 contains one of the...