James Stewart
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Explore the profile of James Stewart including associated specialties, affiliations and a list of published articles.
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131
Citations
1616
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Recent Articles
1.
Stewart J, Krastev D, Brough R, Zatreanu D, Song F, Baxter J, et al.
Oncogene
. 2025 Feb;
44(9):618-629.
PMID: 39939726
Identification of ARID1A/ATR synthetic lethality led to ATR inhibitor phase II trials in ovarian clear cell carcinoma (OCCC), a cancer of unmet need. Using multiple CRISPR-Cas9 mutagenesis and interference screens,...
2.
Landoni J, Erkul S, Laalo T, Goffart S, Kivela R, Skube K, et al.
Nat Commun
. 2024 Sep;
15(1):8066.
PMID: 39277581
High mitochondrial DNA (mtDNA) amount has been reported to be beneficial for resistance and recovery of metabolic stress, while increased mtDNA synthesis activity can drive aging signs. The intriguing contrast...
3.
Beyond Static Planning: Computational Predictive Modeling to Avoid Coronary Artery Occlusion in TAVR
Holst K, Becker T, Magruder J, Yadav P, Stewart J, Rajagopal V, et al.
Ann Thorac Surg
. 2024 Jun;
119(1):145-151.
PMID: 38901627
Background: Coronary artery occlusion (CO) during transcatheter aortic valve replacement (TAVR) is a devastating complication. The objective of this study was to assess the clinical impact of a computational predictive...
4.
Biemans Y, Bach D, Behrouzi P, Horvath S, Kramer C, Liu S, et al.
Age Ageing
. 2024 May;
53(Suppl 2):ii20-ii29.
PMID: 38745494
Background: Heterogeneity in ageing rates drives the need for research into lifestyle secrets of successful agers. Biological age, predicted by epigenetic clocks, has been shown to be a more reliable...
5.
Stewart J, Zayka P, Courter C, Cuk T
J Chem Phys
. 2024 Apr;
160(16).
PMID: 38682740
One of the most reactive intermediates for oxidative reactions is the oxyl radical, an electron-deficient oxygen atom. The discovery of a new vibration upon photoexcitation of the oxygen evolution catalysis...
6.
Ong W, Stewart J, Sahgal A, Soliman H, Tseng C, Detsky J, et al.
Int J Radiat Oncol Biol Phys
. 2024 Apr;
120(3):750-759.
PMID: 38561051
Purpose: We present the final analyses of tumor dynamics and their prognostic significance during a 6-week course of concurrent chemoradiotherapy for glioblastoma in the Glioblastoma Longitudinal Imaging Observational study. Methods...
7.
Tseng C, Zeng K, Mellon E, Soltys S, Ruschin M, Lau A, et al.
Neuro Oncol
. 2024 Mar;
26(12 Suppl 2):S3-S16.
PMID: 38437669
Chemoradiotherapy is the standard treatment after maximal safe resection for glioblastoma (GBM). Despite advances in molecular profiling, surgical techniques, and neuro-imaging, there have been no major breakthroughs in radiotherapy (RT)...
8.
Stewart J, Sahgal A, Hudson J, Lau A, Keller B, Chen H, et al.
Med Phys
. 2023 Dec;
51(5):3597-3603.
PMID: 38088935
Background: The radiotherapy process relies on several metrics in determining a notion of "distance" from one three-dimensional region-of-interest (ROI) to another. The majority are symmetric (or commutative) and do not...
9.
Stewart J, Shawon J, Ali M, Williams B, Shahinuzzaman A, Rupa S, et al.
J Pept Sci
. 2023 Nov;
30(4):e3553.
PMID: 38031661
The main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays an important role in viral replication and transcription and received great attention as a vital target for...
10.
Campbell S, Stewart J, Quail G, Withey G, Smith S, Hanson J
Am J Trop Med Hyg
. 2023 Nov;
109(6):1238-1241.
PMID: 37962328
The clinical manifestations of leptospirosis range from mild to life-threatening and can impact on multiple organ systems. A wide array of neurological manifestations of leptospirosis have been reported, although the...