James Prestegard
Overview
Explore the profile of James Prestegard including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
161
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Recent Articles
1.
Raman S, Lange O, Rossi P, Tyka M, Wang X, Aramini J, et al.
Science
. 2010 Feb;
327(5968):1014-8.
PMID: 20133520
Conventional protein structure determination from nuclear magnetic resonance data relies heavily on side-chain proton-to-proton distances. The necessary side-chain resonance assignment, however, is labor intensive and prone to error. Here we...
2.
Zheng S, Kaur G, Wang H, Li M, Macnaughtan M, Yang X, et al.
J Med Chem
. 2008 Dec;
51(24):7673-88.
PMID: 19049349
Phosphodiesterase 4 catalyzes the hydrolysis of cyclic AMP and is a target for the development of anti-inflammatory agents. We have designed and synthesized a series of phenyl alkyl ketones as...