James O Schenk
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Explore the profile of James O Schenk including associated specialties, affiliations and a list of published articles.
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24
Citations
235
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Recent Articles
1.
Zhang X, Chiu V, Stoica G, Lungu G, Schenk J, Hill Jr H
Anal Chem
. 2014 Feb;
86(6):3075-83.
PMID: 24548008
Electrospray ionization ion mobility mass spectrometry (ESI-IMMS) was used to study the striatal metabolomes in a Parkinson's like disease (PD-like) rat model. Striatal tissue samples from Berlin Druckrey IV (BD-IV)...
2.
Sanchez E, Hayes R, Barr J, Lewis K, Webb B, Subramanian A, et al.
Drug Alcohol Depend
. 2013 Jul;
133(2):344-51.
PMID: 23876860
Background: Cocaine-related deaths are continuously rising and its overdose is often associated with lethal cardiotoxic effects. Methods And Results: Our approach, employing isothermal titration calorimetry (ITC) and light scattering in...
3.
Kaplan K, Chiu V, Lukus P, Zhang X, Siems W, Schenk J, et al.
Anal Bioanal Chem
. 2013 Jan;
405(6):1959-68.
PMID: 23314481
We report results of studies of global and targeted neuronal metabolomes by ambient pressure ion mobility mass spectrometry. The rat frontal cortex, striatum, and thalamus were sampled from control nontreated...
4.
Chiu V, Schenk J
Curr Drug Abuse Rev
. 2012 Sep;
5(3):227-42.
PMID: 22998621
Addiction to methamphetamine (METH) is thought to be mediated by dopaminergic effects in the reward pathway in the brain via the A10 dopaminergic pathway. Herein we describe an overview of...
5.
Stoica G, Lungu G, Bjorklund N, Taglialatela G, Zhang X, Chiu V, et al.
J Neurochem
. 2012 May;
122(4):812-22.
PMID: 22639889
Neuronal protein α-synuclein (α-syn) is an essential player in the development of neurodegenerative diseases called synucleinopathies. A spontaneous autosomal recessive rat model for neurodegeneration was developed in our laboratory. These...
6.
Chiu V, Lukus P, Doyle J, Schenk J
Anal Biochem
. 2011 Aug;
418(1):58-65.
PMID: 21801709
An unstirred layer (USL) exists at the interface of solids with solutions. Thus, the particles in brain tissue preparations possess a USL as well as at the surface of a...
7.
Pearson J, Dahal U, Rock D, Peng C, Schenk J, Joswig-Jones C, et al.
Arch Biochem Biophys
. 2011 May;
511(1-2):69-79.
PMID: 21530484
The metabolic stability of a drug is an important property that should be optimized during drug design and development. Nitrogen incorporation is hypothesized to increase the stability by coordination of...
8.
Schumacher P, Woods N, Doyle J, Schenk J, Clark S
Anal Chem
. 2011 Apr;
83(12):4788-93.
PMID: 21526841
Field detection and quantification of f-elements is an important problem in radioanalytical chemistry requiring small, portable devices. Here, characterization of a 10 μm Hg film carbon fiber disk microelectrode to...
9.
Hagan C, Schenk J, Neumaier J
Synapse
. 2011 Mar;
65(10):1015-23.
PMID: 21437992
Although many studies assert that the serotonin (5-HT) transporter (SERT) is the predominant mechanism controlling extracellular 5-HT concentrations, accumulating evidence suggests that low affinity, high capacity transport mechanisms may contribute...
10.
Schumacher P, Fitzgerald K, Schenk J, Clark S
Anal Chem
. 2011 Jan;
83(4):1388-93.
PMID: 21271692
An evaluation using paraffin oil based, Acheson 38 carbon paste electrodes modified with α-hydroxyisobutyric acid (HIBA) to preconcentrate f-elements cathodically is described. The modified paste was made by directly mixing...