James N Cobley
Overview
Explore the profile of James N Cobley including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
561
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cobley J, Chatzinikolaou P, Schmidt C
Redox Biol
. 2025 Feb;
81:103523.
PMID: 39929052
The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. However, most current site-centric paradigms fail to capture the nonlinear and...
2.
Margaritelis N, Cobley J, Nastos G, Papanikolaou K, Bailey S, Kritsiligkou P, et al.
Free Radic Biol Med
. 2024 Aug;
224:62-77.
PMID: 39147071
Despite the overwhelming number of sports supplements on the market, only seven are currently recognized as effective. Biological functions are largely regulated through redox reactions, yet no comprehensive analysis of...
3.
Cobley J
Am J Physiol Cell Physiol
. 2024 Aug;
327(3):C844-C866.
PMID: 39099422
Cysteine redox proteoforms define the diverse molecular states that proteins with cysteine residues can adopt. A protein with one cysteine residue must adopt one of two binary proteoforms: reduced or...
4.
Cobley J, Margaritelis N, Chatzinikolaou P, Nikolaidis M, Davison G
Antioxidants (Basel)
. 2024 Jul;
13(7).
PMID: 39061945
Formidable and often seemingly insurmountable conceptual, technical, and methodological challenges hamper the measurement of oxidative stress in humans. For instance, fraught and flawed methods, such as the thiobarbituric acid reactive...
5.
Cobley J
Redox Biol
. 2023 Oct;
67:102936.
PMID: 37875063
Oxidative stress is biochemically complex. Like primary colours, specific reactive oxygen species (ROS) and antioxidant inputs can be mixed to create unique "shades" of oxidative stress. Even a minimal redox...
6.
Tuncay A, Crabtree D, Muggeridge D, Husi H, Cobley J
Free Radic Biol Med
. 2023 May;
204:252-265.
PMID: 37192685
The antibody-linked oxi-state assay (ALISA) for quantifying target-specific cysteine oxidation can benefit specialist and non-specialist users. Specialists can benefit from time-efficient analysis and high-throughput target and/or sample n-plex capacities. The...
7.
Cobley J
Bioessays
. 2023 May;
45(7):e2200248.
PMID: 37147790
A single protein molecule with one or more cysteine residues can occupy a plurality of unique residue and oxidation-chemotype specified proteoforms that I term oxiforms. In binary reduced or oxidised...
8.
Bellissimo C, Delfinis L, Hughes M, Turnbull P, Gandhi S, DiBenedetto S, et al.
Am J Physiol Cell Physiol
. 2023 Jan;
324(5):C1141-C1157.
PMID: 36689672
Duchenne muscular dystrophy (DMD) is associated with distinct mitochondrial stress responses. Here, we aimed to determine whether the prospective mitochondrial-enhancing compound Olesoxime, prevents early-stage mitochondrial stress in limb and respiratory...
9.
Muggeridge D, Crabtree D, Tuncay A, Megson I, Davison G, Cobley J
Free Radic Biol Med
. 2022 Feb;
182:73-78.
PMID: 35217176
New readily accessible systemic redox biomarkers are needed to understand the biological roles reactive oxygen species (ROS) play in humans because overtly flawed, technically fraught, and unspecific assays severely hamper...
10.
Tuncay A, Noble A, Guille M, Cobley J
Free Radic Biol Med
. 2022 Feb;
181:118-129.
PMID: 35131446
Unravelling how reactive oxygen species regulate fundamental biological processes is hampered by the lack of an accessible microplate technique to quantify target-specific protein thiol redox state in percentages and moles....