James M Otis
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Explore the profile of James M Otis including associated specialties, affiliations and a list of published articles.
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31
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1401
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Recent Articles
1.
Clarke R, Grant R, Woods S, Pagoota B, Buchmaier S, Bordieanu B, et al.
bioRxiv
. 2024 Jul;
PMID: 38979314
Corticostriatal projection neurons from prelimbic medial prefrontal cortex to the nucleus accumbens core critically regulate drug-seeking behaviors, yet the underlying encoding dynamics whereby these neurons contribute to drug seeking remain...
2.
Paniccia J, Vollmer K, Green L, Grant R, Winston K, Buchmaier S, et al.
Neuron
. 2023 Dec;
112(5):772-785.e9.
PMID: 38141605
Lack of behavioral suppression typifies substance use disorders, yet the neural circuit underpinnings of drug-induced behavioral disinhibition remain unclear. Here, we employ deep-brain two-photon calcium imaging in heroin self-administering mice,...
3.
Vollmer K, Green L, Grant R, Winston K, Doncheck E, Bowen C, et al.
Nat Commun
. 2023 Aug;
14(1):4733.
PMID: 37550296
No abstract available.
4.
Kokane S, Cole R, Bordieanu B, Ray C, Haque I, Otis J, et al.
J Neurosci
. 2023 Apr;
43(22):4019-4032.
PMID: 37094933
Dysregulation of the input from the prefrontal cortex (PFC) to the nucleus accumbens (NAc) contributes to cue-induced opioid seeking but the heterogeneity in, and regulation of, prelimbic (PL)-PFC to NAc...
5.
Vollmer K, Green L, Grant R, Winston K, Doncheck E, Bowen C, et al.
Nat Commun
. 2022 Nov;
13(1):6865.
PMID: 36369508
Suppression of dangerous or inappropriate reward-motivated behaviors is critical for survival, whereas therapeutic or recreational opioid use can unleash detrimental behavioral actions and addiction. Nevertheless, the neuronal systems that suppress...
6.
Paniccia J, Otis J, Scofield M
Comput Struct Biotechnol J
. 2022 Aug;
20:4146-4156.
PMID: 36016711
Astrocytes are critical components of neural circuits positioned in close proximity to the synapse, allowing them to rapidly sense and respond to neuronal activity. One repeatedly observed biomarker of astroglial...
7.
Siemsen B, Barry S, Vollmer K, Green L, Brock A, Westphal A, et al.
Front Cell Neurosci
. 2022 Mar;
16:844243.
PMID: 35281297
Background: Prelimbic cortical projections to the nucleus accumbens core are critical for cue-induced cocaine seeking, but the identity of the accumbens neuron(s) targeted by this projection, and the transient neuroadaptations...
8.
Vollmer K, Doncheck E, Grant R, Winston K, Romanova E, Bowen C, et al.
Front Behav Neurosci
. 2021 Nov;
15():744715.
PMID: 34776891
Multiphoton microscopy is one of several new technologies providing unprecedented insight into the activity dynamics and function of neural circuits. Unfortunately, some of these technologies require experimentation in head-restrained animals,...
9.
Grant R, Doncheck E, Vollmer K, Winston K, Romanova E, Siegler P, et al.
Elife
. 2021 Jun;
10.
PMID: 34184635
Non-overlapping cell populations within dorsomedial prefrontal cortex (dmPFC), defined by gene expression or projection target, control dissociable aspects of reward seeking through unique activity patterns. However, even within these defined...
10.
McGinty J, Otis J
Front Behav Neurosci
. 2020 Nov;
14:590528.
PMID: 33177999
The paraventricular thalamic nucleus (PVT) is highly interconnected with brain areas that control reward-seeking behavior. Despite this known connectivity, broad manipulations of PVT often lead to mixed, and even opposing,...