James M Fleckenstein
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Explore the profile of James M Fleckenstein including associated specialties, affiliations and a list of published articles.
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68
Citations
1715
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Recent Articles
1.
Fleckenstein J, Najjar S, Zimmermann W, Hauck C, Nguyen Q, Mejias-Luque R, et al.
Eur J Clin Invest
. 2024 Dec;
54 Suppl 2:e14355.
PMID: 39674873
No abstract available.
2.
Berndsen Z, Akhtar M, Thapa M, Vickers T, Schmitz A, Torres J, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012241.
PMID: 39283948
Enterotoxigenic Escherichia coli (ETEC) cause hundreds of millions of cases of infectious diarrhea annually, predominantly in children from low-middle income regions. Notably, in children, as well as volunteers challenged with...
3.
Sheikh A, Ganguli D, Vickers T, Singer B, Foulke-Abel J, Akhtar M, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(38):e2410679121.
PMID: 39264739
Enterotoxigenic (ETEC) cause hundreds of millions of diarrheal illnesses annually ranging from mildly symptomatic cases to severe, life-threatening cholera-like diarrhea. Although ETEC are associated with long-term sequelae including malnutrition, the...
4.
Anthonymuthu S, Sabui S, Manzon K, Sheikh A, Fleckenstein J, Said H
Am J Physiol Cell Physiol
. 2024 Sep;
327(5):C1163-C1177.
PMID: 39246143
This study examined the effect of exposure of small and large intestinal epithelial cells to the bacterial lipopolysaccharide (LPS) on uptake of free form of vitamin B1, i.e., thiamin. The...
5.
Sheikh A, Ganguli D, Vickers T, Singer B, Foulke-Abel J, Akhtar M, et al.
bioRxiv
. 2024 Aug;
PMID: 39091797
Enterotoxigenic (ETEC) cause hundreds of millions of diarrheal illnesses annually ranging from mildly symptomatic cases to severe, life-threatening cholera-like diarrhea. Although ETEC are associated with long-term sequelae including malnutrition, the...
6.
Berndsen Z, Akhtar M, Thapa M, Vickers T, Schmitz A, Torres J, et al.
bioRxiv
. 2024 May;
PMID: 38766097
Enterotoxigenic (ETEC) cause hundreds of millions of cases of infectious diarrhea annually, predominantly in children from low-middle income regions. Notably, in children, as well as human volunteers challenged with ETEC,...
7.
Sabui S, Anthonymuthu S, Ramamoorthy K, Skupsky J, Jennings T, Rahmatpanah F, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 May;
327(1):G36-G46.
PMID: 38713615
Humans and mammals obtain vitamin B1 from dietary and gut microbiota sources. A considerable amount of the microbiota-generated vitamin exists in the form of thiamine pyrophosphate (TPP), and colonocytes are...
8.
Kuhlmann F, Grigura V, Vickers T, Prouty M, Iannotti L, Dulience S, et al.
Microorganisms
. 2023 Sep;
11(9).
PMID: 37764065
Enterotoxigenic Escherichia coli (ETEC) are common causes of infectious diarrhea among young children of low-and middle-income countries (LMICs) and travelers to these regions. Despite their significant contributions to the morbidity...
9.
Anthonymuthu S, Sabui S, Lee K, Sheikh A, Fleckenstein J, Said H
Am J Physiol Cell Physiol
. 2023 Jul;
325(3):C758-C769.
PMID: 37519229
This study investigated the effect of the bacterial endotoxin lipopolysaccharide (LPS) on colonic uptake of thiamin pyrophosphate (TPP), the biologically active form of vitamin B1 that is generated by gut...
10.
Ntui C, Fleckenstein J, Schubert W
PLoS One
. 2023 Jun;
18(6):e0287100.
PMID: 37343026
Enterotoxigenic Escherichia coli (ETEC) is a diarrhoeal pathogen associated with high morbidity and mortality especially among young children in developing countries. At present, there is no vaccine for ETEC. One...