James M Cunningham
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Explore the profile of James M Cunningham including associated specialties, affiliations and a list of published articles.
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23
Citations
1284
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Recent Articles
11.
Radoshitzky S, Warfield K, Chi X, Dong L, Kota K, Bradfute S, et al.
J Virol
. 2011 Jun;
85(17):8502-13.
PMID: 21697477
With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and "cuevaviruses") cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP(1,2), to bind...
12.
Shedlock D, Bailey M, Popernack P, Cunningham J, Burton D, Sullivan N
Virology
. 2010 Mar;
401(2):228-35.
PMID: 20304456
Human Ebola virus causes severe hemorrhagic fever disease with high mortality and there is no vaccine or treatment. Antibodies in survivors occur early, are sustained, and can delay infection when...
13.
Smith J, Cunningham J
PLoS Pathog
. 2008 Feb;
3(12):e198.
PMID: 18260686
According to current models of retrovirus infection, receptor binding to the surface subunit (SU) of the envelope glycoprotein (Env) triggers a conformational change in the transmembrane subunit (TM) that mediates...
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Chandran K, Sullivan N, Felbor U, Whelan S, Cunningham J
Science
. 2005 Apr;
308(5728):1643-5.
PMID: 15831716
Ebola virus (EboV) causes rapidly fatal hemorrhagic fever in humans and there is currently no effective treatment. We found that the infection of African green monkey kidney (Vero) cells by...
17.
Rosales A, Cunningham J, Bone A, Green I, Green M
Free Radic Res
. 2004 Sep;
38(7):665-74.
PMID: 15453631
Treatment of cultured rat pancreatic islets of Langerhans with the combined cytokines interleukin-1beta (IL-1beta), interferon gamma (IFN gamma) and tumour necrosis factor alpha (TNF alpha) leads to DNA damage including...
18.
Schuurmans C, Armant O, Nieto M, Stenman J, Britz O, Klenin N, et al.
EMBO J
. 2004 Jul;
23(14):2892-902.
PMID: 15229646
Neocortical projection neurons, which segregate into six cortical layers according to their birthdate, have diverse morphologies, axonal projections and molecular profiles, yet they share a common cortical regional identity and...
19.
Sigfrid L, Cunningham J, Beeharry N, Borg L, Rosales Hernandez A, Carlsson C, et al.
J Mol Med (Berl)
. 2004 Mar;
82(5):325-35.
PMID: 15007513
It has been proposed that low activities of antioxidant enzymes in pancreatic beta cells may increase their susceptibility to autoimmune attack. We have therefore used the spontaneously diabetic BB/S rat...
20.
Smith J, Mothes W, Blacklow S, Cunningham J
J Virol
. 2004 Jan;
78(3):1403-10.
PMID: 14722295
The spring-loaded model stipulates that influenza virus infection is coupled to the transition of the virus hemagglutinin (HA) from a metastable conformation to a highly stable conformation at low pH....