James L Roberts
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Explore the profile of James L Roberts including associated specialties, affiliations and a list of published articles.
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35
Citations
963
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Recent Articles
1.
Dayeh M, Livadiotis G, Aminian F, Cheng K, Roberts J, Viswasam N, et al.
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32326309
The association between plasma cholesterol levels and the development of dementia continues to be an important topic of discussion in the scientific community, while the results in the literature vary...
2.
Miller G, Silverman A, Roberts J, Wendong K, Gibson M
Cell Transplant
. 2017 Feb;
2(3):251-257.
PMID: 28148370
The hypogonadal (HPG) mouse is a mutant that lacks a functional gonadotropin-releasing hormone (GnRH) gene. In this study, female HPG mice received bilateral intrahypothalamic implants of an immortalized GnRH-secreting cell...
3.
Bockus A, Smith L, Grice A, Ali O, Young C, Mobley W, et al.
J Am Chem Soc
. 2016 Dec;
138(50):16549-16552.
PMID: 27998093
This paper describes the design and synthesis of a conjugate (Q7R) comprising the synthetic host cucurbit[7]uril (Q7) linked to the fluorescent dye tetramethylrhodamine (TMR), and the characterization of its optical...
4.
Bains M, Roberts J
Neurosci Lett
. 2015 Nov;
610:79-85.
PMID: 26520464
Astrocytes regulate neuronal homeostasis and have been implicated in affecting the viability and functioning of surrounding neurons under stressed and injured conditions. Previous data from our lab suggests indirect actions...
5.
Rowan M, Berg K, Roberts J, Hargreaves K, Clarke W
J Pharmacol Exp Ther
. 2014 Apr;
349(3):526-32.
PMID: 24706985
Numerous studies have demonstrated that females have a higher risk of experiencing several pain disorders with either greater frequency or severity than males. Although the mechanisms that underlie this sex...
6.
Mott N, Pinceti E, Rao Y, Przybycien-Szymanska M, Prins S, Shults C, et al.
Mol Cell Proteomics
. 2014 Jan;
13(3):760-79.
PMID: 24390426
Recent clinical evidence suggests that the neuroprotective and beneficial effects of hormone therapy may be limited by factors related to age and reproductive status. The patient's age and length of...
7.
Biju K, Santacruz R, Chen C, Zhou Q, Yao J, Rohrabaugh S, et al.
Neurosci Lett
. 2013 Jan;
535:24-9.
PMID: 23295906
Although neurotrophic factors have long been recognized as potent agents for protecting against neuronal degeneration, clinical success in treating Parkinson's disease and other neurodegenerative disorders has been hindered by difficulties...
8.
Cheng B, Martinez A, Morado J, Scofield V, Roberts J, Maffi S
Neurochem Int
. 2012 Nov;
62(1):31-42.
PMID: 23142153
Inhibition of proteasome activity and the resulting protein accumulation are now known to be important events in the development of many neurological disorders, including Alzheimer's and Parkinson's diseases. Abnormal or...
9.
Cunningham R, Macheda T, Watts L, Poteet E, Singh M, Roberts J, et al.
Horm Behav
. 2011 Sep;
60(5):617-24.
PMID: 21907204
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by dopamine neuron loss in the nigrostriatal pathway that shows greater incidence in men than women. The mechanisms underlying this gender...
10.
Cheng B, Maffi S, Martinez A, Villarreal Acosta Y, Morales L, Roberts J
Mol Cell Neurosci
. 2011 May;
47(3):181-90.
PMID: 21545837
The proteasome is an enzyme complex responsible for targeted intracellular proteolysis. Alterations in proteasome-mediated protein clearance have been implicated in the pathogenesis of aging, Alzheimer's disease (AD) and Parkinson's disease...