James J Ashton
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Explore the profile of James J Ashton including associated specialties, affiliations and a list of published articles.
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Articles
67
Citations
404
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Recent Articles
1.
Green Z, Ashton J
Aliment Pharmacol Ther
. 2024 Oct;
60(11-12):1609-1610.
PMID: 39367672
No abstract available.
2.
Noble A, Adams A, Nowak J, Cheng G, Nayak K, Quinn A, et al.
J Crohns Colitis
. 2024 Oct;
PMID: 39365013
The genetic contribution to inflammatory bowel disease (IBD) encompassing both Crohn's disease (CD) and ulcerative colitis (UC), accounts for around 20% of disease variance, highlighting the need to characterise environmental...
3.
Coelho T, Cheng G, Lewis S, Ashton J, Barakat F, Driscoll K, et al.
Inflamm Bowel Dis
. 2024 Jul;
31(2):362-375.
PMID: 39011784
Background: Thiopurine drugs are effective treatment options in inflammatory bowel disease and other conditions but discontinued in some patients due to toxicity. Methods: We investigated thiopurine-induced toxicity in a pediatric...
4.
Coelho T, Cheng G, Vazquez Lopez F, Ashton J, Beattie R, Ennis S
Inflamm Bowel Dis
. 2024 Jul;
30(10):1928-1930.
PMID: 39011772
No abstract available.
5.
Ashton J, Satsangi J, Uhlig H
Gastroenterology
. 2024 Apr;
167(2):205-208.
PMID: 38604541
No abstract available.
6.
Green Z, Ashton J, Rodrigues A, Spray C, Howarth L, Mallikarjuna A, et al.
Inflamm Bowel Dis
. 2024 Feb;
30(12):2271-2279.
PMID: 38372691
Background: Pediatric inflammatory bowel disease (pIBD) incidence has increased over the last 25 years. We aim to report contemporaneous trends across the South West United Kingdom. Methods: Data were provided...
7.
Seaby E, Leggatt G, Cheng G, Thomas N, Ashton J, Stafford I, et al.
Genet Med
. 2024 Jan;
26(4):101073.
PMID: 38245859
Purpose: The 100,000 Genomes Project diagnosed a quarter of affected participants, but 26% of diagnoses were not on the applied gene panel(s); with many being de novo variants. Assessing biallelic...
8.
Green Z, Beattie R, Ashton J
Transl Pediatr
. 2023 Nov;
12(10):1853-1874.
PMID: 37969128
Background And Objective: The landscape of paediatric inflammatory bowel disease (pIBD) continues to evolve in an era of increasing incidence. There have been rapid developments in understanding, as we begin...
9.
Stafford I, Ashton J, Mossotto E, Cheng G, Beattie R, Ennis S
J Crohns Colitis
. 2023 May;
17(10):1672-1680.
PMID: 37205778
Background: Inflammatory bowel disease [IBD] is a chronic inflammatory disorder with two main subtypes: Crohn's disease [CD] and ulcerative colitis [UC]. Prompt subtype diagnosis enables the correct treatment to be...
10.
Ashton J, Gurung A, Davis C, Seaby E, Coelho T, Batra A, et al.
J Pediatr Gastroenterol Nutr
. 2023 Apr;
77(1):70-78.
PMID: 37079872
Background/objective: Heterogeneity and chronicity of Crohn disease (CD) make prediction of outcomes difficult. To date, no longitudinal measure can quantify burden over a patient's disease course, preventing assessment and integration...