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James Hatfield

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Articles 20
Citations 213
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Recent Articles
1.
Tobi M, Khoury N, Al-Subee O, Sethi S, Talwar H, Kam M, et al.
Biomolecules . 2024 Sep; 14(9). PMID: 39334948
The primary pre-neoplastic lesion of the lower esophagus in the vicinity of the gastroesophageal junction (GEJ) is any Barrett's esophageal lesions (BE), and esophageal neoplasia has increased in the US...
2.
Tobi M, Weinstein D, Kim M, Hatfield J, Sochacki P, Levi E, et al.
Curr Oncol . 2023 Sep; 30(9):7950-7963. PMID: 37754493
Background: We evaluated the phenotype of sporadic gastric cancer based on HP status and binding of a tumor risk marker monoclonal, Adnab-9. Methods: We compared a familial GC kindred with...
3.
Tobi M, Kim M, Weinstein D, Rambus M, Hatfield J, Adsay N, et al.
Dig Dis Sci . 2012 Sep; 58(3):744-50. PMID: 23001406
Background And Aim: Sporadic pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer. No proven screening strategies are available and frequent cross-sectional imaging studies (CT/MRI) are impractical even in patients...
4.
Farhana L, Dawson M, Das J, Murshed F, Xia Z, Hadden T, et al.
J Oncol . 2012 May; 2012:796729. PMID: 22570653
Pancreatic carcinoma has a dismal prognosis as it often presents as locally advanced or metastatic. We have found that exposure to adamantyl-substituted retinoid-related (ARR) compounds 3-Cl-AHPC and AHP3 resulted in...
5.
Katona I, Zhang X, Bai Y, Shy M, Guo J, Yan Q, et al.
Eur J Neurosci . 2011 Mar; 33(8):1401-10. PMID: 21410794
Loss of function of the FIG4 gene causes Charcot-Marie-Tooth disease (CMT)-4J with many features also found in motor neuron disease (MND). Mechanisms for the degeneration are unknown. We investigated this...
6.
Farhana L, Dawson M, Xia Z, Aboukameel A, Xu L, Liu G, et al.
Mol Cancer Ther . 2010 Nov; 9(11):2903-13. PMID: 21062916
The adamantyl-substituted retinoid-related (ARR) compounds 3-Cl-AHPC and AHP3 induce apoptosis in vitro and in vivo in a newly established human acute myelogenous leukemia (AML) cell line, FFMA-AML, and in the...
7.
Tobi M, Kim M, Zimmer R, Hatfield J, Kam M, Khoury N, et al.
Dig Dis Sci . 2010 Jul; 56(2):397-405. PMID: 20645001
Background And Aim: A major cause of cancer-related deaths is the development of liver metastasis. To better understand the metastatic process, we studied the cotton top tamarin as an animal...
8.
Berk R, Crossland W, Kosir M, Yu M, Wang Y, Alousi S, et al.
Exp Eye Res . 2009 Aug; 89(6):1035-8. PMID: 19651123
Platelet basic protein (PBP) and several of its derivatives are known to express a wide range of biological characteristics. It is the precursor of connective tissue activating peptide (CTAP-III), beta...
9.
Marepaily R, Micheals D, Sloan A, Hatfield J, Adsay V, Joyrich R, et al.
Dig Dis Sci . 2008 Nov; 54(1):188-90. PMID: 18985450
We describe a case with prolonged survival of 2 years in a female patient with pancreatic ductal adenocarcinoma who, at diagnosis, already had liver spread and eventually succumbed to brain...
10.
Walsh M, Ampasala D, Hatfield J, Heide R, Suer S, Rishi A, et al.
Am J Pathol . 2008 Jun; 173(2):385-99. PMID: 18583311
Focal adhesion kinase (FAK) regulates cell migration, proliferation, and apoptosis. FAK protein is reduced at the edge of migrating gut epithelial sheets in vitro, but it has not been characterized...