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James H Millonig

Explore the profile of James H Millonig including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 624
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Recent Articles
1.
McDermott C, Gao Z, Mirmajlesi A, Ntim C, Kimbark K, Thomas D, et al.
bioRxiv . 2025 Mar; PMID: 40060402
Neurodevelopmental disorders result from interactions between genetic predisposition and environmental risk factors, with infancy being the most vulnerable period. We designed a longitudinal study to determine how short-term antibiotic exposure...
2.
Joshi J, Lerner A, Scallo F, Grumet A, Matteson P, Millonig J, et al.
Cell Rep . 2024 Jul; 43(8):114543. PMID: 39067023
Mechanistic Target of Rapamycin Complex 1 (mTORC1) is a master metabolic regulator that is active in nearly all proliferating eukaryotic cells; however, it is unclear whether mTORC1 activity changes throughout...
3.
Prem S, Dev B, Peng C, Mehta M, Alibutud R, Connacher R, et al.
Elife . 2024 Mar; 13. PMID: 38525876
Autism spectrum disorder (ASD) is defined by common behavioral characteristics, raising the possibility of shared pathogenic mechanisms. Yet, vast clinical and etiological heterogeneity suggests personalized phenotypes. Surprisingly, our iPSC studies...
4.
Joshi J, Lerner A, Scallo F, Grumet A, Matteson P, Millonig J, et al.
bioRxiv . 2024 Feb; PMID: 38370755
Mechanistic Target of Rapamycin Complex 1 (mTORC1) is a master metabolic regulator that stimulates anabolic cell growth while suppressing catabolic processes such as autophagy. mTORC1 is active in most, if...
5.
Salamon I, Park Y, Miskic T, Kopic J, Matteson P, Page N, et al.
Nat Commun . 2023 Sep; 14(1):6025. PMID: 37758766
Abnormalities in neocortical and synaptic development are linked to neurodevelopmental disorders. However, the molecular and cellular mechanisms governing initial synapse formation in the prenatal neocortex remain poorly understood. Using polysome...
6.
Connacher R, Williams M, Prem S, Yeung P, Matteson P, Mehta M, et al.
Stem Cell Reports . 2022 Jul; 17(7):1786. PMID: 35830838
No abstract available.
7.
Connacher R, Williams M, Prem S, Yeung P, Matteson P, Mehta M, et al.
Stem Cell Reports . 2022 May; 17(6):1380-1394. PMID: 35623351
Neural precursor cell (NPC) dysfunction has been consistently implicated in autism. Induced pluripotent stem cell (iPSC)-derived NPCs from two autism groups (three idiopathic [I-ASD] and two 16p11.2 deletion [16pDel]) were...
8.
Prem S, Millonig J, DiCicco-Bloom E
Adv Neurobiol . 2020 Jun; 25:109-153. PMID: 32578146
Despite decades of study, elucidation of the underlying etiology of complex developmental disorders such as autism spectrum disorder (ASD), schizophrenia (SCZ), intellectual disability (ID), and bipolar disorder (BPD) has been...
9.
Turkalj L, Mehta M, Matteson P, Prem S, Williams M, Connacher R, et al.
Adv Neurobiol . 2020 Jun; 25:79-107. PMID: 32578145
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is remarkably heterogeneous at the clinical, neurobiological, and genetic levels. ASD can also affect language, a uniquely human capability, and is...
10.
Williams M, Prem S, Zhou X, Matteson P, Yeung P, Lu C, et al.
J Vis Exp . 2018 Mar; (133). PMID: 29553565
Human brain development proceeds through a series of precisely orchestrated processes, with earlier stages distinguished by proliferation, migration, and neurite outgrowth; and later stages characterized by axon/dendrite outgrowth and synapse...