James H Adair
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Explore the profile of James H Adair including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
603
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Recent Articles
1.
Abraham T, Armold M, McGovern C, Harms J, Darok M, Gigliotti C, et al.
Biomedicines
. 2024 May;
12(5).
PMID: 38790986
The poor prognosis for pancreatic ductal adenocarcinoma (PDAC) patients is due in part to the highly fibrotic nature of the tumors that impedes delivery of therapeutics, including nanoparticles (NPs). Our...
2.
Castro R, Adair J, Mastro A, Neuberger T, Matters G
Nanomedicine (Lond)
. 2024 Feb;
19(8):723-735.
PMID: 38420919
Vascular cell adhesion molecule-1 (VCAM-1) was identified over 2 decades ago as an endothelial adhesion receptor involved in leukocyte recruitment and cell-based immune responses. In atherosclerosis, a chronic inflammatory disease...
3.
van der Vlies A, Ghasemi M, Adair B, Adair J, Gomez E, Hasegawa U
Adv Healthc Mater
. 2022 Dec;
12(6):e2201836.
PMID: 36495554
Hydrogen sulfide (H S) is a gaseous signaling molecule in the human body and has attracted attention in cancer therapy due to its regulatory roles in cancer cell proliferation and...
4.
Abraham T, McGovern C, Linton S, Wilczynski Z, Adair J, Matters G
Int J Nanomedicine
. 2021 Mar;
16:2297-2309.
PMID: 33776434
Purpose: Accurate tumor identification and staging can be difficult. Aptamer-targeted indocyanine green (ICG)-nanoparticles can enhance near-infrared fluorescent imaging of pancreatic and prostate tumors and could improve early cancer detection. This...
5.
Bussard K, Gigliotti C, Adair B, Snyder J, Gigliotti N, Loc W, et al.
Nanomedicine
. 2021 Mar;
34:102383.
PMID: 33722692
Calcium phosphosilicate nanoparticles (CPSNPs) are bioresorbable nanoparticles that can be bioconjugated with targeting molecules and encapsulate active agents and deliver them to tumor cells without causing damage to adjacent healthy...
6.
Tang X, Loc W, Dong C, Matters G, Butler P, Kester M, et al.
Nanomedicine (Lond)
. 2017 Sep;
12(19):2367-2388.
PMID: 28868970
Breast cancer is a major ongoing public health issue among women in both developing and developed countries. Significant progress has been made to improve the breast cancer treatment in the...
7.
Jariwala S, Lewis G, Bushman Z, Adair J, Donahue H
3D Print Addit Manuf
. 2017 Aug;
2(2):56-64.
PMID: 28804734
Additive manufacturing technologies, including three-dimensional printing (3DP), have unlocked new possibilities for bone tissue engineering. Long-term regeneration of normal anatomic structure, shape, and function is clinically important subsequent to bone...
8.
Loc W, Linton S, Wilczynski Z, Matters G, McGovern C, Abraham T, et al.
Nanomedicine
. 2017 Jul;
13(7):2313-2324.
PMID: 28673852
Drug resistant cancers like pancreatic ductal adenocarcinoma (PDAC) are difficult to treat, and nanoparticle drug delivery systems can overcome some of the limitations of conventional systemic chemotherapy. In this study,...
9.
Clawson G, Abraham T, Pan W, Tang X, Linton S, McGovern C, et al.
Nucleic Acid Ther
. 2016 Oct;
27(1):23-35.
PMID: 27754762
Pancreatic ductal adenocarcinomas (PDACs) constitutively express the G-protein-coupled cholecystokinin B receptor (CCKBR). In this study, we identified DNA aptamers (APs) that bind to the CCKBR and describe their characterization and...
10.
Loc W, Smith J, Matters G, Kester M, Adair J
World J Gastroenterol
. 2014 Oct;
20(40):14717-25.
PMID: 25356034
With the incidence reports of pancreatic cancer increasing every year, research over the last several decades has been focused on the means to achieve early diagnosis in patients that are...