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James G Linneman

Explore the profile of James G Linneman including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 636
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Recent Articles
1.
Joo Y, Pacheco J, Thompson W, Rasmussen-Torvik L, Rasmussen L, Lin F, et al.
PLoS One . 2023 May; 18(5):e0283553. PMID: 37196047
Objective: Diverticular disease (DD) is one of the most prevalent conditions encountered by gastroenterologists, affecting ~50% of Americans before the age of 60. Our aim was to identify genetic risk...
2.
Kawai V, Shi M, Liu G, Feng Q, Wei W, Chung C, et al.
Lupus . 2021 May; 30(8):1264-1272. PMID: 33977795
Objectives: To test the hypothesis that genetic predisposition to systemic lupus erythematosus (SLE) increases the risk of cardiometabolic disorders. Methods: Using 41 single nucleotide polymorphisms (SNPs) associated with SLE, we...
3.
Hellwege J, Stallings S, Torstenson E, Carroll R, Borthwick K, Brilliant M, et al.
Sci Rep . 2019 Apr; 9(1):6077. PMID: 30988330
Benign prostatic hyperplasia (BPH) results in a significant public health burden due to the morbidity caused by the disease and many of the available remedies. As much as 70% of...
4.
Mosley J, Benson M, Smith J, Melander O, Ngo D, Shaffer C, et al.
Circulation . 2018 Dec; 138(22):2469-2481. PMID: 30571344
Background: Proteomic approaches allow measurement of thousands of proteins in a single specimen, which can accelerate biomarker discovery. However, applying these technologies to massive biobanks is not currently feasible because...
5.
Almoguera B, Vazquez L, Mentch F, March M, Connolly J, Peissig P, et al.
J Allergy Clin Immunol . 2018 Nov; 143(3):1229-1231. PMID: 30414857
No abstract available.
6.
Mosley J, Feng Q, Wells Q, Van Driest S, Shaffer C, Edwards T, et al.
Nat Commun . 2018 Sep; 9(1):3522. PMID: 30166544
Defining the full spectrum of human disease associated with a biomarker is necessary to advance the biomarker into clinical practice. We hypothesize that associating biomarker measurements with electronic health record...
7.
Mosley J, Shoemaker M, Wells Q, Darbar D, Shaffer C, Edwards T, et al.
Circ Cardiovasc Genet . 2017 Apr; 10(2). PMID: 28416512
Background: One potential use for the PR interval is as a biomarker of disease risk. We hypothesized that quantifying the shared genetic architectures of the PR interval and a set...
8.
Jackson K, Mbagwu M, Pacheco J, Baldridge A, Viox D, Linneman J, et al.
BMC Infect Dis . 2016 Nov; 16(1):684. PMID: 27855652
Background: Community associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is one of the most common causes of skin and soft tissue infections in the United States, and a variety of genetic host...
9.
Mosley J, Van Driest S, Wells Q, Shaffer C, Edwards T, Bastarache L, et al.
Circ Cardiovasc Genet . 2016 Oct; 9(6):521-530. PMID: 27780847
Background: Continued reductions in morbidity and mortality attributable to ischemic heart disease (IHD) require an understanding of the changing epidemiology of this disease. We hypothesized that we could use genetic...
10.
Verma S, Cooke Bailey J, Lucas A, Bradford Y, Linneman J, Hauser M, et al.
PLoS Genet . 2016 Sep; 12(9):e1006186. PMID: 27623284
Primary open angle glaucoma (POAG) is a complex disease and is one of the major leading causes of blindness worldwide. Genome-wide association studies have successfully identified several common variants associated...