James F Cnota
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Explore the profile of James F Cnota including associated specialties, affiliations and a list of published articles.
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62
Citations
493
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Recent Articles
1.
Dong W, Jin S, Sierant M, Lu Z, Li B, Lu Q, et al.
Proc Natl Acad Sci U S A
. 2025 Mar;
122(10):e2419992122.
PMID: 40030011
Variants with large effect contribute to congenital heart disease (CHD). To date, recessive genotypes (RGs) have commonly been implicated through anecdotal ascertainment of consanguineous families and candidate gene-based analysis; the...
2.
Geva T, Wald R, Bucholz E, Cnota J, McElhinney D, Mercer-Rosa L, et al.
Circulation
. 2024 Nov;
150(25):e689-e707.
PMID: 39569497
Right ventricular outflow dysfunction, manifesting as stenosis, regurgitation, or both, is nearly universal in patients with repaired tetralogy of Fallot, precipitating a complex pathophysiological cascade that leads to increasing rates...
3.
Hogue S, Mehdizadeh-Shrifi A, Kulshrestha K, Cnota J, Divanovic A, Ricci M, et al.
World J Pediatr Congenit Heart Surg
. 2024 Sep;
15(6):714-721.
PMID: 39252613
With significant advancements in fetal cardiac imaging, patients with complex congenital heart disease (CHD) carrying a high risk for postnatal demise are now being diagnosed earlier. We sought to assess...
4.
Vandewouw M, Norris-Brilliant A, Rahman A, Assimopoulos S, Morton S, Kushki A, et al.
Neuroimage
. 2024 Jul;
297:120721.
PMID: 38968977
Individuals with congenital heart disease (CHD) have an increased risk of neurodevelopmental impairments. Given the hypothesized complexity linking genomics, atypical brain structure, cardiac diagnoses and their management, and neurodevelopmental outcomes,...
5.
Tseng S, Anderson S, DeFranco E, Rossi R, Divanovic A, Cnota J
JACC Adv
. 2024 Jun;
1(4):100125.
PMID: 38939712
Background: Maternal risk factors for fetal congenital heart disease (CHD) may also be associated with delivery complications in the mother. Objectives: This study aimed to determine the prevalence of and...
6.
Shalhoub K, Heydarian H, Hanke S, Cnota J, Stein L, Tepe B, et al.
J Am Heart Assoc
. 2024 Jun;
13(12):e032055.
PMID: 38860404
Background: We sought to measure frequency of achieving an optimal outcome after stage 1 palliation (S1P) for hypoplastic left heart syndrome and variants, determine factors associated with optimal outcomes, and...
7.
Hill G, Wu D, Ferguson M, Flores S, Ginde S, Hill K, et al.
JACC Adv
. 2024 Apr;
3(3).
PMID: 38606347
Background: Utilization of Fontan fenestration varies considerably by center. Objectives: Using a multicenter Pediatric Heart Network dataset linking surgical and preoperative hemodynamic variables, the authors evaluated factors associated with use...
8.
Raga L, Heydarian H, Winlaw D, Zang H, Cnota J, Ollberding N, et al.
Ann Thorac Surg
. 2024 Mar;
118(2):459-467.
PMID: 38513984
Background: Morbidity and mortality after the Norwood procedure remains high. Shunt size selection is not standardized and the impact of shunt size on outcomes is poorly understood. The Single Ventricle...
9.
Goldberg C, Trachtenberg F, Gaynor J, Mahle W, Ravishankar C, Schwartz S, et al.
Circulation
. 2023 Oct;
148(17):1330-1339.
PMID: 37795623
Objective: In the SVR trial (Single Ventricle Reconstruction), newborns with hypoplastic left heart syndrome were randomly assigned to receive a modified Blalock-Taussig-Thomas shunt (mBTTS) or a right ventricle-to-pulmonary artery shunt...
10.
Miller T, Hernandez E, Gaynor J, Russell M, Newburger J, Chung W, et al.
Commun Med (Lond)
. 2023 Sep;
3(1):127.
PMID: 37758840
Background: Recent large-scale sequencing efforts have shed light on the genetic contribution to the etiology of congenital heart defects (CHD); however, the relative impact of genetics on clinical outcomes remains...