James E Womack
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Explore the profile of James E Womack including associated specialties, affiliations and a list of published articles.
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68
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1579
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Recent Articles
1.
Hughes J, Skaletsky H, Pyntikova T, Koutseva N, Raudsepp T, Brown L, et al.
Genome Res
. 2020 Nov;
30(12):1716-1726.
PMID: 33208454
Studies of Y Chromosome evolution have focused primarily on gene decay, a consequence of suppression of crossing-over with the X Chromosome. Here, we provide evidence that suppression of X-Y crossing-over...
2.
Lee M, Dobson L, Davis B, Skow L, Derr J, Womack J
J Hered
. 2018 May;
109(5):598-603.
PMID: 29718298
Antimicrobial peptides (AMPs) are a class of natural peptides with varying numbers of amino acids. They are principal components of innate immunity in vertebrates, encoding natural antibiotics and providing a...
3.
Lee M, Bornelov S, Andersson L, Lamont S, Chen J, Womack J
Proc Natl Acad Sci U S A
. 2016 Nov;
113(48):13815-13820.
PMID: 27849592
Defensins constitute an evolutionary conserved family of cationic antimicrobial peptides that play a key role in host innate immune responses to infection. Defensin genes generally reside in complex genomic regions...
4.
Lee M, Jang H, Rengaraj D, Yang S, Han J, Lamont S, et al.
BMC Vet Res
. 2016 Oct;
12(1):231.
PMID: 27737668
Background: Host defence peptides are a diverse group of small, cationic peptides and are important elements of the first line of defense against pathogens in animals. Expression and functional analysis...
5.
Chen J, Yang C, Tizioto P, Huang H, Lee M, Payne H, et al.
PLoS One
. 2016 Jul;
11(7):e0158882.
PMID: 27409794
Unlike the genomes of many mammals that have a single NK-lysin gene, the cattle genome contains a family of four genes, one of which is expressed preferentially in the lung....
6.
Chen J, Huddleston J, Buckley R, Malig M, Lawhon S, Skow L, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
112(52):E7223-9.
PMID: 26668394
NK-lysin is an antimicrobial peptide and effector protein in the host innate immune system. It is coded by a single gene in humans and most other mammalian species. In this...
7.
Busch C, Callicott R, Peters C, Morrill J, Womack J
J Hered
. 2015 Nov;
106(6):728-33.
PMID: 26546799
The Rift Valley Fever virus (RVFV) presents an epidemic and epizootic threat in sub-Saharan Africa, Egypt, and the Arabian Peninsula, and has furthermore recently gained attention as a potential weapon...
8.
Neibergs H, Seabury C, Wojtowicz A, Wang Z, Scraggs E, Kiser J, et al.
BMC Genomics
. 2014 Dec;
15:1164.
PMID: 25534905
Background: Bovine respiratory disease complex (BRDC) is an infectious disease of cattle that is caused by a combination of viral and/or bacterial pathogens. Selection for cattle with reduced susceptibility to...
9.
Soh Y, Alfoldi J, Pyntikova T, Brown L, Graves T, Minx P, et al.
Cell
. 2014 Nov;
159(4):800-13.
PMID: 25417157
We sequenced the MSY (male-specific region of the Y chromosome) of the C57BL/6J strain of the laboratory mouse Mus musculus. In contrast to theories that Y chromosomes are heterochromatic and...
10.
Van Eenennaam A, Neibergs H, Seabury C, Taylor J, Wang Z, Scraggs E, et al.
Anim Health Res Rev
. 2014 Nov;
15(2):157-60.
PMID: 25384903
The Bovine Respiratory Disease Coordinated Agricultural Project (BRD CAP) is a 5-year project funded by the United States Department of Agriculture (USDA), with an overriding objective to use the tools...