James E Porter
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Explore the profile of James E Porter including associated specialties, affiliations and a list of published articles.
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39
Citations
760
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Recent Articles
1.
McGregor B, Raihan M, Brishti A, Hur J, Porter J
Front Mol Neurosci
. 2025 Feb;
18:1544971.
PMID: 40018011
Introduction: Growing recognition of microglia's role in neurodegenerative disorders has accentuated the need to characterize microglia profiles and their influence on pathogenesis. To understand changes observed in the microglial profile...
2.
Biggane J, Xu K, Goldenstein B, Davis K, Luger E, Davis B, et al.
J Recept Signal Transduct Res
. 2022 Aug;
42(6):580-587.
PMID: 35984443
The mechanism underlying the antiepileptic actions of norepinephrine (NE) is unclear with conflicting results. Our objectives are to conclusively delineate the specific adrenergic receptor (AR) involved in attenuating hippocampal CA3...
3.
Raihan M, Espelien B, Hanson C, McGregor B, Velaris N, Alvine T, et al.
Prostaglandins Leukot Essent Fatty Acids
. 2022 Jun;
182:102452.
PMID: 35690004
Prostanoids are potent inflammatory mediators that play a regulatory role in the innate immune activation of the adaptive immune response to determine the duration of protection against infection. We aim...
4.
McGregor B, Schommer J, Guo K, Raihan M, Ghribi O, Hur J, et al.
Neuroscience
. 2022 May;
492:108.
PMID: 35513021
No abstract available.
5.
Raihan M, Espelien B, McGregor B, Hanson C, Brishti A, Velaris N, et al.
Vaccines (Basel)
. 2022 Feb;
10(2).
PMID: 35214778
BscF is a type III secretion system (T3SS) needle protein from and has previously been shown to induce a sufficient Th1 and Th17 response in human monocytes and mice as...
6.
Raihan M, McGregor B, Velaris N, Brishti A, Hur J, Porter J
Methods Protoc
. 2021 Dec;
4(4).
PMID: 34940397
Microglia, the resident brain immune effectors cells, show dynamic activation level changes for most neuropsychiatric diseases, reflecting their complex regulatory function and potential as a therapeutic target. Emerging single-cell molecular...
7.
McGregor B, Schommer J, Guo K, Raihan M, Ghribi O, Hur J, et al.
Neuroscience
. 2021 Jun;
468:186-198.
PMID: 34082066
Synucleinopathy disorders are characterized by aggregates of α-synuclein (α-syn), which engage microglia to elicit a neuroinflammatory response. Here, we determined the gene expression and DNA methylation changes in microglia induced...
8.
Rashmi , More S, Wang Q, Vomhof-DeKrey E, Porter J, Basson M
Pharmacol Res Perspect
. 2021 Mar;
9(2):e00737.
PMID: 33715263
Focal adhesion kinase (FAK) regulates gastrointestinal epithelial restitution and healing. ZINC40099027 (Zn27) activates cellular FAK and promotes intestinal epithelial wound closure in vitro and in mice. However, whether Zn27 activates...
9.
McGregor B, Eid S, Rumora A, Murdock B, Guo K, Anda-Jauregui G, et al.
Sci Rep
. 2018 Dec;
8(1):17678.
PMID: 30518872
Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes. In this study, we employed a systems biology approach to identify DPN-related transcriptional pathways conserved across human...
10.
Cilz N, Porter J, Lei S
MethodsX
. 2017 Oct;
4:360-371.
PMID: 29071214
Understanding how neuromodulators influence synaptic transmission and intrinsic excitability within the entorhinal cortex (EC) is critical to furthering our understanding of the molecular and cellular aspects of this region. Organotypic...