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James E Jan

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Articles 19
Citations 422
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Recent Articles
1.
Jan J, Bax M, Owens J, Ipsiroglu O, Wasdell M
Eur J Paediatr Neurol . 2012 Jan; 16(5):403-12. PMID: 22264650
This article reviews circadian rhythm sleep disorders (CRSDs) of children with neurodevelopmental disabilities. These sleep disturbances frequently occur in this population but they are misunderstood and under diagnosed. The causes...
2.
Jan J, Ribary U, Wong P, Reiter R, Bax M, Wasdell M
J Clin Neurophysiol . 2011 Mar; 28(2):165-9. PMID: 21399521
The objective of this prospective observational study was to assess the association between dysrhythmia of EEG background (disturbance of cerebral connectivity) and sleep difficulties. Sixty children, aged 4 to 12...
3.
Jan J, Reiter R, Wong P, Bax M, Ribary U, Wasdell M
J Pineal Res . 2011 Jan; 50(3):233-40. PMID: 21210841
Melatonin, which is known to have sleep-promoting properties, has no morpho-physiological barriers and readily enters neurons and their subcellular compartments from both the blood and cerebrospinal fluid. It has multiple...
4.
Jan J, Asante K, Conry J, Fast D, Bax M, Ipsiroglu O, et al.
Int J Pediatr . 2010 Aug; 2010. PMID: 20706655
This article describes the combined clinical experience of a multidisciplinary group of professionals on the sleep disturbances of children with fetal alcohol spectrum disorders (FASD) focusing on sleep hygiene interventions....
5.
Jan J, Reiter R, Bax M, Ribary U, Freeman R, Wasdell M
Eur J Paediatr Neurol . 2010 Jun; 14(5):380-90. PMID: 20554229
Short-term sleep loss is known to cause temporary difficulties in cognition, behaviour and health but the effects of persistent sleep deprivation on brain development have received little or no attention....
6.
Jan J, Owens J, Weiss M, Johnson K, Wasdell M, Freeman R, et al.
Pediatrics . 2008 Dec; 122(6):1343-50. PMID: 19047255
Sleep disturbances in children with neurodevelopmental disabilities are common and have a profound effect on the quality of life of the child, as well as the entire family. Although interventions...
7.
Jan J, Reiter R, Wasdell M, Bax M
J Pineal Res . 2008 Sep; 46(1):1-7. PMID: 18761566
The thalamus has a strong nonphotic influence on sleep, circadian rhythmicity, pineal melatonin production, and secretion. The opening of the sleep gate for nonrapid eye movement sleep is a thalamic...
8.
Jan J, Wasdell M
Dev Med Child Neurol . 2008 Jul; 50(7):558. PMID: 18611209
No abstract available.
9.
Wasdell M, Jan J, Bomben M, Freeman R, Rietveld W, Tai J, et al.
J Pineal Res . 2007 Dec; 44(1):57-64. PMID: 18078449
The purpose of this study was to determine the efficacy of controlled-release (CR) melatonin in the treatment of delayed sleep phase syndrome and impaired sleep maintenance of children with neurodevelopmental...
10.
Carr R, Wasdell M, Hamilton D, Weiss M, Freeman R, Tai J, et al.
J Pineal Res . 2007 Oct; 43(4):351-9. PMID: 17910603
To date, there have been no prospective long-term studies of melatonin therapy in children. We report here data from a prospective follow-up study of 44 children with neurodevelopmental disabilities and...