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James E Hassell

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Recent Articles
1.
Niemeyer C, Merle L, Bubak A, Baxter B, Gentile Polese A, Colon-Reyes K, et al.
bioRxiv . 2024 Oct; PMID: 39386674
Importance: This study sheds light on how herpes simplex virus type 1 (HSV-1) spreads within the brain after infecting the nasal passages. Our data reveals the distinct pattern of HSV-1...
2.
Plas S, Tuna T, Bayer H, Juliano V, Sweck S, Arellano Perez A, et al.
Front Behav Neurosci . 2024 Feb; 18:1352797. PMID: 38370858
The regulation of fear memories is critical for adaptive behaviors and dysregulation of these processes is implicated in trauma- and stress-related disorders. Treatments for these disorders include pharmacological interventions as...
3.
Hassell J, Baratta M, Fallon I, Siebler P, Karns B, Nguyen K, et al.
Brain Behav Immun . 2022 Sep; 107:1-15. PMID: 36108946
Stress-related psychiatric disorders including anxiety disorders, mood disorders, and trauma and stressor-related disorders, such as posttraumatic stress disorder (PTSD), affect millions of people world-wide each year. Individuals with stress-related psychiatric...
4.
Foxx C, Heinze J, Gonzalez A, Vargas F, Baratta M, Elsayed A, et al.
Front Physiol . 2021 Jan; 11:524833. PMID: 33469429
Previous studies demonstrate that NCTC 11659 (), a soil-derived bacterium with anti-inflammatory and immunoregulatory properties, is a potentially useful countermeasure against negative outcomes to stressors. Here we used male C57BL/6NCrl...
5.
Bubak A, Beseler C, Como C, Coughlan C, Johnson N, Hassell J, et al.
J Infect Dis . 2020 Aug; 223(7):1284-1294. PMID: 32809013
Background: Varicella zoster virus (VZV) vasculopathy is characterized by persistent arterial inflammation leading to stroke. Studies show that VZV induces amyloid formation that may aggravate vasculitis. Thus, we determined if...
6.
Bubak A, Como C, Coughlan C, Johnson N, Hassell J, Mescher T, et al.
J Infect Dis . 2019 Oct; 221(7):1088-1097. PMID: 31665341
Background: Herpes zoster is linked to amyloid-associated diseases, including dementia, macular degeneration, and diabetes mellitus, in epidemiological studies. Thus, we examined whether varicella-zoster virus (VZV)-infected cells produce amyloid. Methods: Production...
7.
Novick A, Forster G, Hassell J, Davies D, Scholl J, Renner K, et al.
Neuropharmacology . 2015 Jun; 97:194-200. PMID: 26056032
Being bullied during adolescence is associated with later mental illnesses characterized by deficits in cognitive tasks mediated by prefrontal cortex (PFC) dopamine (DA). Social defeat of adolescent male rats, as...
8.
Li H, Scholl J, Tu W, Hassell J, Watt M, Forster G, et al.
Eur J Neurosci . 2014 Sep; 40(11):3684-92. PMID: 25234335
Withdrawal from amphetamine increases anxiety and reduces the ability to cope with stress, which are factors that are believed to contribute to drug relapse. Stress-induced serotonergic transmission in the central...