James E Faber
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Explore the profile of James E Faber including associated specialties, affiliations and a list of published articles.
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69
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2687
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Recent Articles
1.
Faber J
J Cereb Blood Flow Metab
. 2025 Mar;
:271678X251322378.
PMID: 40072222
Collateral blood vessels are unique, naturally occurring endogenous bypass vessels that provide alternative pathways for oxygen delivery in obstructive arterial conditions and diseases. Surprisingly however, the capacity of the collateral...
2.
Faber J
J Cereb Blood Flow Metab
. 2025 Feb;
:271678X251317880.
PMID: 39901795
It has been estimated that approximately two million neurons, sixteen billion synapses and twelve kilometers of axons are lost each minute following anterior large-vessel stroke. The level of collateral blood...
3.
Faber J, Zhang H, Xenakis J, Bell T, Hock P, Pardo-Manuel de Villena F, et al.
J Cereb Blood Flow Metab
. 2023 Aug;
43(11):1983-2004.
PMID: 37572089
Collateral blood flow varies greatly among humans for reasons that remain unclear, resulting in significant differences in ischemic tissue damage. A similarly large variation has also been found in mice...
4.
Faber J, Zhang H, Xenakis J, Bell T, Hock P, Pardo-Manuel de Villena F, et al.
bioRxiv
. 2023 Jul;
PMID: 37398475
Collateral blood flow varies greatly among humans for reasons that remain unclear, resulting in significant differences in ischemic tissue damage. A similarly large variation has also been found in mice...
5.
Khan A, De Boever P, Gerrits N, Akhtar N, Saqqur M, Ponirakis G, et al.
PLoS One
. 2022 May;
17(5):e0267837.
PMID: 35511879
Objectives: Pial collateral blood flow is a major determinant of the outcomes of acute ischemic stroke. This study was undertaken to determine whether retinal vessel metrics can predict the pial...
6.
Aghajanian A, Zhang H, Buckley B, Wittchen E, Ma W, Faber J
J Mol Cell Cardiol
. 2020 Oct;
150:1-11.
PMID: 33038388
Rationale: Collateral vessels lessen myocardial ischemia when acute or chronic coronary obstruction occurs. It has long been assumed that although native (pre-existing) collaterals enlarge in obstructive disease, new collaterals do...
7.
Yanagisawa T, Zhang H, Suzuki T, Kamio Y, Takizawa T, Morais A, et al.
Stroke
. 2020 Sep;
51(10):3083-3094.
PMID: 32912097
Background And Purpose: Intracranial aneurysm formation and rupture risk are, in part, determined by genetic factors and sex. To examine their role, we compared 3 mouse strains commonly used in...
8.
Faber J, Storz J, Cheviron Z, Zhang H
J Cereb Blood Flow Metab
. 2020 Jul;
41(4):731-744.
PMID: 32703056
Collateral number/density varies widely in brain and other tissues among strains of mice due to differences in genetic background. Recent studies have shown that prolonged exposure to reduced atmospheric oxygen...
9.
Hendrix P, Sofoluke N, Adams M, Kunaprayoon S, Zand R, Kolinovsky A, et al.
PLoS One
. 2020 Jun;
15(6):e0235122.
PMID: 32584873
The MGP single nucleotide polymorphism (SNP) rs1800801 has previously been associated with recurrent ischemic stroke in a Spanish cohort. Here, we tested for association of this SNP with ischemic stroke...
10.
Zhang H, Rzechorzek W, Aghajanian A, Faber J
J Cereb Blood Flow Metab
. 2020 May;
40(9):1806-1822.
PMID: 32423327
Pial collaterals provide protection in stroke. Evidence suggests their formation late during gestation (collaterogenesis) is driven by reduced oxygen levels in the cerebral watersheds. The purpose of this study was...