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James Deeds

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Articles 6
Citations 249
Followers 0
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Recent Articles
1.
Grauel A, Nguyen B, Ruddy D, Laszewski T, Schwartz S, Chang J, et al.
Nat Commun . 2020 Dec; 11(1):6315. PMID: 33298926
Despite the increasing interest in targeting stromal elements of the tumor microenvironment, we still face tremendous challenges in developing adequate therapeutics to modify the tumor stromal landscape. A major obstacle...
2.
Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al.
Elife . 2016 May; 5. PMID: 27183006
The TMPRSS2:ERG gene fusion is common in androgen receptor (AR) positive prostate cancers, yet its function remains poorly understood. From a screen for functionally relevant ERG interactors, we identify the...
3.
Vicario R, Peg V, Morancho B, Zacarias-Fluck M, Zhang J, Martinez-Barriocanal A, et al.
PLoS One . 2015 Jun; 10(6):e0129876. PMID: 26075403
A chromosomal region that includes the gene encoding HER2, a receptor tyrosine kinase (RTK), is amplified in 20% of breast cancers. Although these tumors tend to respond to drugs directed...
4.
Wiederschain D, Chen L, Johnson B, Bettano K, Jackson D, Taraszka J, et al.
Mol Cell Biol . 2007 Apr; 27(13):4968-79. PMID: 17452456
Bmi-1 and Mel-18 are structural homologues that belong to the Polycomb group of transcriptional regulators and are believed to stably maintain repression of gene expression by altering the state of...
5.
Berger A, Baege A, Guillemette T, Deeds J, Meyer R, Disbrow G, et al.
Am J Pathol . 2002 Aug; 161(2):603-10. PMID: 12163384
Human papillomaviruses (HPVs) infect cervical epithelial cells and induce both benign and precancerous lesions. High-risk HPVs promote the development of cervical cancer in vivo and can immortalize cervical epithelial cells...
6.
Lamarcq L, Deeds J, Ginzinger D, Perry J, Padmanabha S, Smith-McCune K
J Mol Diagn . 2002 May; 4(2):97-102. PMID: 11986400
Specific assays capable of distinguishing normal and atypical cervical changes from pre-cancerous lesions are direly needed to improve screening for cervical cancer. Specific genes transcripts that are up-regulated in dysplastic...