James D Schmelzer
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Explore the profile of James D Schmelzer including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
716
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Recent Articles
1.
Singer W, Schmeichel A, Shahnawaz M, Schmelzer J, Sletten D, Gehrking T, et al.
Ann Neurol
. 2021 Apr;
89(6):1212-1220.
PMID: 33881777
Objective: To explore the role of alpha-synuclein (αSyn) oligomers and neurofilament light chain (NfL) in cerebrospinal fluid (CSF) of patients with pure autonomic failure (PAF) as markers of future phenoconversion...
2.
Singer W, Schmeichel A, Shahnawaz M, Schmelzer J, Boeve B, Sletten D, et al.
Ann Neurol
. 2020 Jun;
88(3):503-512.
PMID: 32557811
Objective: To explore the role of alpha-synuclein (αSyn) oligomers and neurofilament light chain (NFL) in cerebrospinal fluid (CSF) as markers of early multiple system atrophy (MSA) and to contrast findings...
3.
Corfits J, Singer W, Sandroni P, Fealey R, Coon E, Benarroch E, et al.
Auton Neurosci
. 2019 Nov;
222:102589.
PMID: 31706219
Introduction: Forearm QSWEAT recordings are occasionally absent in females, likely due to high skin resistance. Methods: We identified consecutive subjects with no sudomotor abnormalities but absent/markedly reduced QSWEAT forearm volume,...
4.
Singer W, Dietz A, Zeller A, Gehrking T, Schmelzer J, Schmeichel A, et al.
Neurology
. 2019 Jun;
93(1):e77-e87.
PMID: 31152011
Objective: This phase I/II study sought to explore intrathecal administration of mesenchymal stem cells (MSCs) as therapeutic approach to multiple system atrophy (MSA). Methods: Utilizing a dose-escalation design, we delivered...
5.
Wada N, Singer W, Gehrking T, Sletten D, Schmelzer J, Low P
Clin Sci (Lond)
. 2014 Mar;
127(5):307-13.
PMID: 24597842
The baroreflex plays a key role in human BP (blood pressure) regulation. Its efferent limb consists of a vagal and a sympathetic component. The Valsalva manoeuvre is widely used to...
6.
Yoshii Y, Zhao C, Schmelzer J, Low P, An K, Amadio P
Hand (N Y)
. 2014 Feb;
9(1):52-7.
PMID: 24570638
Background: This study investigated the effects of a series of four hypertonic dextrose injections on the subsynovial connective tissue (SSCT) and median nerve within the carpal tunnel of a rabbit...
7.
Wada N, Singer W, Gehrking T, Sletten D, Schmelzer J, Kihara M, et al.
Muscle Nerve
. 2014 Jan;
50(4):535-40.
PMID: 24477673
Introduction: The Valsalva maneuver (VM) is used widely to quantify the sensitivity of the vagal baroreflex loop (vagal baroreflex sensitivity, BRS_v), but most studies have focused on the heart rate...
8.
Vanhees M, Chikenji T, Thoreson A, Zhao C, Schmelzer J, Low P, et al.
Hand (N Y)
. 2014 Jan;
8(1):54-9.
PMID: 24426893
Background: The most prominent nonneurological finding in the common compression neuropathy carpal tunnel syndrome (CTS) is fibrosis of the subsynovial connective tissue (SSCT). Recently, a rabbit model of CTS has...
9.
Ta L, Schmelzer J, Bieber A, Loprinzi C, Sieck G, Brederson J, et al.
PLoS One
. 2013 Jan;
8(1):e54161.
PMID: 23326593
Background: Chemotherapy-induced neuropathy is the principle dose limiting factor requiring discontinuation of many chemotherapeutic agents, including cisplatin and oxaliplatin. About 30 to 40% of patients receiving chemotherapy develop pain and...
10.
Moriya T, Zhao C, Cha S, Schmelzer J, Low P, An K, et al.
Hand (N Y)
. 2012 Dec;
6(4):399-407.
PMID: 23204967
Background: The etiology of carpal tunnel syndrome (CTS) remains idiopathic in many cases. Noninflammatory fibrosis of the subsynovial connective tissue (SSCT) within the carpal tunnel is common in CTS, and...