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James D McCully

Explore the profile of James D McCully including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 2000
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Recent Articles
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Brestoff J, Singh K, Aquilano K, Becker L, Berridge M, Boilard E, et al.
Nat Metab . 2025 Jan; 7(1):53-67. PMID: 39820558
Intercellular mitochondria transfer is an evolutionarily conserved process in which one cell delivers some of their mitochondria to another cell in the absence of cell division. This process has diverse...
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Doulamis I, Tzani A, Alemany V, Nomoto R, Celik A, Recco D, et al.
Sci Rep . 2024 Dec; 14(1):31236. PMID: 39732955
Heart transplantation remains the ultimate treatment strategy for neonates and children with medically refractory end-stage heart failure and utilization of donors after circulatory death (DCD) can expand th donor pool....
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Bechet N, Celik A, Mittendorfer M, Wang Q, Huzevka T, Kjellberg G, et al.
J Heart Lung Transplant . 2024 Nov; 44(3):448-459. PMID: 39536924
Background: Ischemia-reperfusion injury (IRI) plays a crucial role in the development of primary graft dysfunction (PGD) following lung transplantation. A promising novel approach to optimize donor organs before transplantation and...
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Arroum T, Hish G, Burghardt K, Ghamloush M, Bazzi B, Mrech A, et al.
J Strength Cond Res . 2024 Jun; 38(7):1189-1199. PMID: 38900170
Arroum, T, Hish, GA, Burghardt, KJ, Ghamloush, M, Bazzi, B, Mrech, A, Morse, PT, Britton, SL, Koch, LG, McCully, JD, Hüttemann, M, and Malek, MH. Mitochondria transplantation: Rescuing innate muscle...
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Bodenstein D, Siebiger G, Zhao Y, Clasky A, Mukkala A, Beroncal E, et al.
Stem Cell Res Ther . 2024 May; 15(1):157. PMID: 38816774
Mitochondrial transplantation and transfer are being explored as therapeutic options in acute and chronic diseases to restore cellular function in injured tissues. To limit potential immune responses and rejection of...
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Arroum T, Hish G, Burghardt K, McCully J, Huttemann M, Malek M
Biomolecules . 2024 Apr; 14(4). PMID: 38672509
Background: Mitochondria are the 'powerhouses of cells' and progressive mitochondrial dysfunction is a hallmark of aging in skeletal muscle. Although different forms of exercise modality appear to be beneficial to...
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McCully J, Del Nido P, Emani S
Front Cardiovasc Med . 2024 Jan; 10:1268814. PMID: 38162128
Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our...
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Alemany V, Recco D, Emani S, Del Nido P, McCully J
J Vis Exp . 2023 Nov; (201). PMID: 37982519
The protocol here provides a simple, highly replicable methodology to induce in situ acute regional myocardial ischemia in the rabbit for non-survival and survival experiments. New Zealand White adult rabbit...
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Alemany V, Nomoto R, Saeed M, Celik A, Regan W, Matte G, et al.
J Thorac Cardiovasc Surg . 2023 May; 167(1):e6-e21. PMID: 37211245
Objective: Mitochondrial transplantation has been shown to preserve myocardial function and viability in adult porcine hearts donated after circulatory death (DCD) . Herein, we investigate the efficacy of mitochondrial transplantation...