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James D Anholm

Explore the profile of James D Anholm including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 143
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Recent Articles
1.
Zavorsky G, Elkinany S, Alismail A, Thapamagar S, Terry M, Anholm J, et al.
Physiol Rep . 2025 Feb; 13(5):e70212. PMID: 40012207
This study aimed to evaluate discordance, binary classification, and model fit between race-predicted and race-neutral spirometry prediction equations. Spirometry data from 9506 patients (18-95 years old) self-identifying as White, Black,...
2.
Foster K, Anholm J, Foster G, Thapamagar S, Subedi P
High Alt Med Biol . 2024 Jul; 26(1):13-19. PMID: 38966963
Foster, Katharine, James D. Anholm, Gary Foster, Suman Thapamagar, and Prajan Subedi. Effects of naltrexone on sleep quality and periodic breathing at high altitude. 26:13-19, 2025. This study examined the...
3.
Patrician A, Anholm J, Ainslie P
J Physiol . 2024 Mar; 602(21):5435-5448. PMID: 38534039
Periodic breathing during sleep at high altitude is almost universal among sojourners. Here, in the context of acclimatization and adaptation, we provide a contemporary review on periodic breathing at high...
4.
Zaid A, Thapamagar S, Anholm J, Weaver-Carnahan L, Duong L, Specht L
Chronic Obstr Pulm Dis . 2024 Feb; 11(2):206-215. PMID: 38310543
Background: Dyspnea is frequently a debilitating symptom of chronic obstructive pulmonary disease (COPD). Cannabinoid receptor agonists have the potential to alter dyspnea in these patients. Objective: Our objective was to...
5.
Steele A, Howe C, Gibbons T, Foster K, Williams A, Caldwell H, et al.
Am J Physiol Heart Circ Physiol . 2024 Jan; 326(3):H705-H714. PMID: 38241007
Pentoxifylline is a nonselective phosphodiesterase inhibitor used for the treatment of peripheral artery disease. Pentoxifylline acts through cyclic adenosine monophosphate, thereby enhancing red blood cell deformability, causing vasodilation and decreasing...
6.
Patrician A, Willie C, Hoiland R, Gasho C, Subedi P, Anholm J, et al.
J Cereb Blood Flow Metab . 2023 Mar; 43(7):1166-1179. PMID: 36883428
Cerebral blood flow (CBF) increases during hypoxia to counteract the reduction in arterial oxygen content. The onset of tissue hypoxemia coincides with the stabilization of hypoxia-inducible factor (HIF) and transcription...
7.
Subedi P, Gasho C, Stembridge M, Williams A, Patrician A, Ainslie P, et al.
Exp Physiol . 2022 Nov; 108(1):111-122. PMID: 36404588
New Findings: What is the central question of this study? How does hypoxic pulmonary vasoconstriction and the response to supplemental oxygen change over time at high altitude? What is the...
8.
Chen H, Joshi S, Oberle A, Wong A, Shaz D, Thapamagar S, et al.
Front Physiol . 2022 Jun; 13:914972. PMID: 35733991
Excessive decrease in the flow of the late expiratory portion of a flow volume loop (FVL) or "flattening", reflects small airway dysfunction. The assessment of the flattening is currently determined...
9.
Steele A, Ainslie P, Stone R, Tymko K, Tymko C, Howe C, et al.
High Alt Med Biol . 2022 Mar; 23(2):185-191. PMID: 35231184
Steele, Andrew R., Philip N. Ainslie, Rachel Stone, Kaitlyn Tymko, Courtney Tymko, Connor A. Howe, David MacLeod, James D. Anholm, Christopher Gasho, and Michael M. Tymko. Global REACH 2018: characterizing...
10.
Tymko M, Willie C, Howe C, Hoiland R, Stone R, Tymko K, et al.
J Appl Physiol (1985) . 2022 Jan; 132(2):575-580. PMID: 35023761
High-altitude exposure results in a hyperventilatory-induced respiratory alkalosis followed by renal compensation (bicarbonaturia) to return arterial blood pH (pHa) toward sea-level values. However, acid-base balance has not been comprehensively examined...