James C Nicholson
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Explore the profile of James C Nicholson including associated specialties, affiliations and a list of published articles.
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54
Citations
1341
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Recent Articles
1.
Ferraresso M, Bailey S, Alonso-Crisostomo L, Ward D, Panayi C, Scurlock Z, et al.
Mol Oncol
. 2024 Nov;
PMID: 39522951
MicroRNAs (miRNAs) are short, nonprotein-coding RNAs, and their expression is dysregulated in malignant germ cell tumors (GCTs). Here, we investigated the causes and consequences of downregulated miR-99a-5p/miR-100-5p (functionally identical) and...
2.
Palenzuela G, Schiffler C, Frappaz D, Peyrl A, Gerber N, Kortmann R, et al.
Front Oncol
. 2024 Jul;
14:1421418.
PMID: 39077474
Background: SIOP-CNS-GCT-II European trial was opened for the treatment of patients of any age with central nervous system germ cell tumour (CNS-GCT). Four courses of pre-irradiation chemotherapy were delivered. The...
3.
Green R, Ahmed A, Fleming B, Long A, Behjati S, Trotman J, et al.
Pediatr Dev Pathol
. 2023 Dec;
27(3):260-265.
PMID: 38098239
Wilms tumor (WT) is the commonest cause of renal cancer in children. In Europe, a diagnosis is made for most cases on typical clinical and radiological findings, prior to pre-operative...
4.
Bailey S, Ferraresso M, Alonso-Crisostomo L, Ward D, Smith S, Nicholson J, et al.
Br J Cancer
. 2023 Nov;
129(9):1524.
PMID: 37919375
No abstract available.
5.
Bailey S, Ferraresso M, Alonso-Crisostomo L, Ward D, Smith S, Nicholson J, et al.
Br J Cancer
. 2023 Oct;
129(9):1451-1461.
PMID: 37789102
Background: MiR-371~373 and miR-302/367 cluster over-expression occurs in all malignant germ cell tumours (GCTs), regardless of age (paediatric/adult), site (gonadal/extragonadal), or subtype [seminoma, yolk sac tumour (YST), embryonal carcinoma (EC)]....
6.
Laidlaw S, Alonso-Crisostomo L, Bailey S, Saini H, Molnar A, Nicholson J, et al.
Andrology
. 2022 Oct;
11(4):738-755.
PMID: 36254403
Background: Analyses of small non-coding RNA (ncRNA) expression in malignant germ cell tumours (GCTs) have focused on microRNAs (miRNAs). As GCTs all arise from primordial germ cells, and piwi-interacting RNAs...
7.
Fonseca A, Lobo J, Hazard F, Gell J, Nicholls P, Weiss R, et al.
Br J Cancer
. 2022 Oct;
127(9):1577-1583.
PMID: 36229581
Germ cell tumours (GCTs) are a heterogeneous group of rare neoplasms that present in different anatomical sites and across a wide spectrum of patient ages from birth through to adulthood....
8.
Shabo E, Czech T, Nicholson J, Mallucci C, Mottolese C, Piatelli G, et al.
Cancers (Basel)
. 2022 Jul;
14(14).
PMID: 35884617
Background: CNS germinoma, being marker-negative, are mainly diagnosed by histological examination. These tumors predominantly appear in the suprasellar and/or pineal region. In contrast to the suprasellar region, where biopsy is...
9.
Morana G, Shaw D, MacDonald S, Alapetite C, Ajithkumar T, Bhatia A, et al.
Lancet Oncol
. 2022 Apr;
23(5):e218-e228.
PMID: 35489353
Homogeneous and common objective disease assessments and standardised response criteria are important for better international clinical trials for CNS germ cell tumours. Currently, European protocols differ from those of North...
10.
Trotman J, Armstrong R, Firth H, Trayers C, Watkins J, Allinson K, et al.
Br J Cancer
. 2022 Apr;
127(1):137-144.
PMID: 35449451
Background: Whole-genome sequencing (WGS) of cancers is becoming an accepted component of oncological care, and NHS England is currently rolling out WGS for all children with cancer. This approach was...