James B Fink
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Explore the profile of James B Fink including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
1589
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Recent Articles
1.
Li J, Sheridan C, Alanazi O, Fink J
J Aerosol Med Pulm Drug Deliv
. 2024 Dec;
PMID: 39648821
Aerosol delivery may be enhanced by utilizing an inspiration-synchronized nebulization mode, where nebulization occurs only during inspiration. This study aimed to compare aerosol delivery of albuterol via a prototype of...
2.
Li J, Karabelas P, Gong L, Sheridan C, Fink J
Pediatr Pulmonol
. 2024 Nov;
60(1):e27356.
PMID: 39503177
Background: An inspiration-synchronized vibrating mesh nebulizer (VMN) has been reported to improve aerosol delivery during adult mechanical ventilation. A prototype VMN generating smaller particles was developed. We aimed to compare...
3.
Ari A, Hoops J, Koyuncu A, Fink J
Expert Opin Drug Deliv
. 2024 Aug;
21(7):1103-1114.
PMID: 39104360
Introduction: Transnasal aerosol drug delivery has become widely accepted for treating acutely ill infants, children, and adults. More recently aerosol administration to wider populations receiving high and low-flow nasal oxygen...
4.
Fink J, Stapleton K
J Aerosol Med Pulm Drug Deliv
. 2024 Apr;
37(3):140-156.
PMID: 38683652
Nebulizers generate aerosols from liquid-based solutions and suspensions. Nebulizers are particularly well suited to delivering larger doses of medication than is practical with inhalers and are used with a broad...
5.
Lin H, Fink J, Li J
J Aerosol Med Pulm Drug Deliv
. 2024 Apr;
37(3):125-131.
PMID: 38563958
Some experts recommend specific ventilator settings during nebulization for mechanically ventilated patients, such as inspiratory pause, high inspiratory to expiratory ratio, and so on. However, it is unclear whether those...
6.
Jacquier S, Lin H, Li J, Sheridan C, Karabelas P, Liu J, et al.
J Aerosol Med Pulm Drug Deliv
. 2024 Apr;
37(3):115-124.
PMID: 38563793
During mechanical ventilation (MV), inspired gases require heat and humidification. However, such conditions may be associated with reduced aerosol delivery efficiency. The practice of turning off heated humidification before nebulization...
7.
Dushianthan A, Clark H, Brealey D, Pratt D, Fink J, Madsen J, et al.
Sci Rep
. 2023 Nov;
13(1):20946.
PMID: 38017061
SARS-CoV-2 directly targets alveolar epithelial cells and can lead to surfactant deficiency. Early reports suggested surfactant replacement may be effective in improving outcomes. The aim of the study to assess...
8.
Ari A, Raghavan N, Diaz M, Rubin B, Fink J
Paediatr Respir Rev
. 2023 Sep;
49:14-23.
PMID: 37739833
Pulmonary drug delivery is complex due to several challenges including disease-, patient-, and clinicians-related factors. Although many inhaled medications are available in aerosol medicine, delivering aerosolized medications to patients requires...
9.
Li J, Liu K, Lyu S, Jing G, Dai B, Dhand R, et al.
Ann Intensive Care
. 2023 Jul;
13(1):63.
PMID: 37436585
Background: Clinical practice of aerosol delivery in conjunction with respiratory support devices for critically ill adult patients remains a topic of controversy due to the complexity of the clinical scenarios...
10.
Lima C, Campos S, Bandeira M, Leite W, Brandao D, Fernandes J, et al.
Pharmaceutics
. 2023 May;
15(5).
PMID: 37242708
Background: Little has been reported in terms of clinical outcomes to confirm the benefits of nebulized bronchodilators during mechanical ventilation (MV). Electrical Impedance Tomography (EIT) could be a valuable method...