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James A Whitworth

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Citations 775
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Recent Articles
1.
Fujisawa K, Silcott-Niles C, Simonson P, Lamattina D, Humeres C, Bhattacharyya T, et al.
PLoS Negl Trop Dis . 2021 Jul; 15(7):e0009552. PMID: 34280201
Background: Visceral leishmaniasis (VL) is a zoonotic protozoal vector-borne disease that is a major public health challenge. In Argentina, canine (CVL) and human visceral leishmaniasis (HVL) have recently emerged. There...
2.
Collis S, El-Safi S, Atia A, Bhattacharyya T, Hammad A, den Boer M, et al.
Int J Infect Dis . 2019 Aug; 88:14-20. PMID: 31442631
Objectives: Local health personnel have drawn attention to an apparent increase in incidence and severity of cutaneous leishmaniasis (CL) in Sudan. The objective of this study was to investigate CL...
3.
Churcher T, Pion S, Osei-Atweneboana M, Prichard R, Awadzi K, Boussinesq M, et al.
Proc Natl Acad Sci U S A . 2009 Oct; 106(39):16716-21. PMID: 19805362
Identification of drug resistance before it becomes a public health concern requires a clear distinction between what constitutes a normal and a suboptimal treatment response. A novel method of analyzing...
4.
Freeman E, Weiss H, Glynn J, Cross P, Whitworth J, Hayes R
AIDS . 2005 Dec; 20(1):73-83. PMID: 16327322
Objective: To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection. Background: The increased number of longitudinal studies available since the last...
5.
Yirrell D, Kaleebu P, Morgan D, Hutchinson S, Whitworth J
Int J STD AIDS . 2004 Mar; 15(2):103-6. PMID: 15006072
Our objective was to monitor changes in the subtypes of HIV-1 infecting a rural Ugandan cohort where the spread of HIV-1 is by unprotected heterosexual contact and subtypes A and...
6.
Schmid G, Buve A, Mugyenyi P, Garnett G, Hayes R, Williams B, et al.
Lancet . 2004 Feb; 363(9407):482-8. PMID: 14962531
During the past year, a group has argued that unsafe injections are a major if not the main mode of HIV-1 transmission in sub-Saharan Africa. We review the main arguments...
7.
Orroth K, Korenromp E, White R, Gavyole A, Gray R, Muhangi L, et al.
AIDS . 2003 Dec; 17(18):2653-60. PMID: 14685060
Objective: To determine to what extent the higher impact of treatment for sexually transmitted diseases (STD) on HIV incidence in Mwanza, Tanzania than in Rakai and Masaka, Uganda might be...
8.
Nakiyingi J, Bracher M, Whitworth J, Ruberantwari A, Busingye J, Mbulaiteye S, et al.
AIDS . 2003 Aug; 17(12):1827-34. PMID: 12891069
Objective: To analyse the contribution of maternal survival and HIV status to child (under-5 years) mortality in a rural population cohort in South-west Uganda. Methods: Approximately 10 000 people residing...
9.
Elliott A, Mawa P, Joseph S, Namujju P, Kizza M, Nakiyingi J, et al.
Trans R Soc Trop Med Hyg . 2003 Jul; 97(1):103-8. PMID: 12886815
It has been proposed that helminth infection may exacerbate HIV progression by promoting activation of 'type 2' immune responses. To examine this hypothesis, we investigated helminth infection in a cohort...
10.
Tchilian E, Dawes R, Ramaley P, Whitworth J, Yuldasheva N, Wells R, et al.
Immunogenetics . 2002 Feb; 53(10-11):980-3. PMID: 11862398
The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Abnormal CD45 splicing has...