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James A Draper

Explore the profile of James A Draper including associated specialties, affiliations and a list of published articles. Areas
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Citations 120
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Recent Articles
1.
Williams A, Koves T, Pettway Y, Draper J, Slentz D, Grimsrud P, et al.
iScience . 2022 Jan; 25(1):103635. PMID: 35028529
Nicotinamide riboside supplements (NRS) have been touted as a nutraceutical that promotes cardiometabolic and musculoskeletal health by enhancing nicotinamide adenine dinucleotide (NAD) biosynthesis, mitochondrial function, and/or the activities of NAD-dependent...
2.
Bareja A, Draper J, Katz L, Lee D, Grimsrud P, White J
Mech Ageing Dev . 2021 Feb; 195:111443. PMID: 33529682
Caloric restriction (CR) can prolong aged skeletal muscle function, yet the molecular mechanisms are not completely understood. We performed phosphoproteomic analysis on muscle from young and old mice fed an...
3.
Davidson M, Grimsrud P, Lai L, Draper J, Fisher-Wellman K, Narowski T, et al.
Circ Res . 2020 Jul; 127(8):1094-1108. PMID: 32660330
Rationale: Circumstantial evidence links the development of heart failure to posttranslational modifications of mitochondrial proteins, including lysine acetylation (Kac). Nonetheless, direct evidence that Kac compromises mitochondrial performance remains sparse. Objective:...
4.
Williams A, Koves T, Davidson M, Crown S, Fisher-Wellman K, Torres M, et al.
Cell Metab . 2019 Dec; 31(1):131-147.e11. PMID: 31813822
This study sought to examine the functional significance of mitochondrial protein acetylation using a double knockout (DKO) mouse model harboring muscle-specific deficits in acetyl-CoA buffering and lysine deacetylation, due to...
5.
Fisher-Wellman K, Draper J, Davidson M, Williams A, Narowski T, Slentz D, et al.
Cell Rep . 2019 Feb; 26(6):1557-1572.e8. PMID: 30726738
Acyl CoA metabolites derived from the catabolism of carbon fuels can react with lysine residues of mitochondrial proteins, giving rise to a large family of post-translational modifications (PTMs). Mass spectrometry-based...
6.
Liao K, Jones R, McCarter P, Tunc-Ozdemir M, Draper J, Elston T, et al.
J Theor Biol . 2016 Dec; 414:231-244. PMID: 27923735
Plants tolerate large variations in the intensity of the light environment by controlling the efficiency of solar to chemical energy conversion. To do this, plants have a mechanism to detect...