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James A Coles Jr

Explore the profile of James A Coles Jr including associated specialties, affiliations and a list of published articles. Areas
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Citations 102
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Recent Articles
1.
Seewald M, Coles Jr J, Sigg D, Iaizzo P
Exp Biol Med (Maywood) . 2017 Apr; 242(9):986-995. PMID: 28440739
Ischemic preconditioning has been utilized to protect the heart from ischemia prior to ischemia onset, whereas postconditioning is employed to minimize the consequences of ischemia at the onset of reperfusion....
2.
Singh J, Abraham W, Chung E, Rogers T, Sambelashvili A, Coles Jr J, et al.
Europace . 2013 Sep; 15(11):1622-8. PMID: 24014804
Aims: Adaptive cardiac resynchronization therapy (aCRT) is a novel algorithm for CRT pacing that provides automatic ambulatory selection between synchronized left ventricular (LV) or bi-ventricular (BiV) pacing and optimization of...
3.
Levin V, Razavi M, Coll R, Coles Jr J, Sambelashvili A
Pacing Clin Electrophysiol . 2011 Jan; 34(4):443-9. PMID: 21208227
Background: Echocardiographic optimization of the atrioventricular delay (AV) may result in improvement in cardiac resynchronization therapy (CRT) outcome. Optimal AV has been shown to correlate with interatrial conduction time (IACT)...
4.
Levin V, Nemeth M, Colombowala I, Massumi A, Rasekh A, Cheng J, et al.
J Cardiovasc Electrophysiol . 2007 Feb; 18(3):290-5. PMID: 17313655
Background: Optimizing atrioventricular (AV) delay during biventricular (BiV) pacemaker implantation can require substantial resources. Hence, a simpler method is desirable. We hypothesized that interatrial conduction time (IACT), measured at the...
5.
Viswanathan P, Coles Jr J, Sharma V, Sigg D
Heart Rhythm . 2006 Jul; 3(7):824-31. PMID: 16818216
Background: Normal cardiac rhythm is critically dependent on the sinoatrial (SA) node, the natural biological pacemaker. Although recent studies have focused on the development of "artificial" biological pacemakers using gene...
6.
Cohen M, Brabec S, Shindeldecker B, Laske T, Coles Jr J
Pacing Clin Electrophysiol . 2006 Jun; 29(6):679-81. PMID: 16784436
Limited data exist on the utilization of a transvenous A-sense; V-pace/sense (VDD)pacing system with a chronically retained nonfunctioning endocardial V-sense/pace (VVI)pacing lead. In an acute canine model, no atrial oversensing...
7.
Sigg D, Hiniduma-Lokuge P, Coles Jr J, Falkner P, Rose R, Urban J, et al.
Circulation . 2006 May; 113(20):2383-90. PMID: 16702470
Background: Pharmacological ventricular rate control is an acceptable atrial fibrillation (AF) therapy limited by systemic toxicity. We postulate that focal catheter-based drug delivery into the atrioventricular nodal (AVN) region may...
8.
Hong J, Sigg D, Coles Jr J, Oeltgen P, Harlow H, Soule C, et al.
Muscle Nerve . 2005 Jun; 32(2):200-7. PMID: 15940690
A link between the cardioprotective benefits of pharmacological preconditioning and natural mammalian hibernation is considered to involve the cellular activation of opioid receptors and subsequent opening of K(ATP) channels. In...
9.
Coles Jr J, Sigg D, Iaizzo P
Biochem Pharmacol . 2005 May; 69(11):1553-8. PMID: 15896334
Introduction: Myocardial edema is a clinically relevant problem found in post-ischemic reperfused hearts. The objective of this study was to understand the effects of hetastarch-supplemented cardioplegia on post-ischemic edema and...
10.
Hill A, Laske T, Coles Jr J, Sigg D, Skadsberg N, Vincent S, et al.
Ann Thorac Surg . 2004 Dec; 79(1):168-77. PMID: 15620938
Background: Isolated mammalian hearts have been used in numerous studies that have led to many important discoveries in cardiac physiology, pharmacology, and surgery. Multiple methods of perfusion have been described...