Jamal M Bryant
Overview
Explore the profile of Jamal M Bryant including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
25
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Recent Articles
1.
Ng V, Spencer Z, Neitzel L, Nayak A, Loberg M, Shen C, et al.
Nat Commun
. 2023 Oct;
14(1):6173.
PMID: 37798301
The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human disease. While the ubiquitin ligases that ubiquitylate Wnt receptors are well-characterized,...
2.
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6
Spencer Z, Ng V, Benchabane H, Siddiqui G, Duwadi D, Maines B, et al.
Nat Commun
. 2023 Oct;
14(1):6174.
PMID: 37798281
The control of Wnt receptor abundance is critical for animal development and to prevent tumorigenesis, but the mechanisms that mediate receptor stabilization remain uncertain. We demonstrate that stabilization of the...
3.
Bryant J, Malabanan M, Vanderloop B, Nichols C, Haratipour Z, Poon K, et al.
J Lipid Res
. 2021 May;
62:100081.
PMID: 33933440
Nuclear receptors are transcription factors that bind lipids, an event that induces a structural conformation of the receptor that favors interaction with transcriptional coactivators. The nuclear receptor steroidogenic factor-1 (SF-1,...
4.
Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease
Bryant J, Blind R
J Lipid Res
. 2018 Sep;
60(2):299-311.
PMID: 30201631
Phosphoinositide membrane signaling is critical for normal physiology, playing well-known roles in diverse human pathologies. The basic mechanisms governing phosphoinositide signaling within the nucleus, however, have remained deeply enigmatic owing...