Jakub Neradil
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Explore the profile of Jakub Neradil including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
603
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Recent Articles
1.
Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, et al.
Cancer Cell
. 2025 Mar;
PMID: 40086436
PDGFRA is crucial to tumorigenesis and frequently genomically altered in high-grade glioma (HGG). In a comprehensive dataset of pediatric HGG (n = 261), we detect PDGFRA mutations and/or amplifications in...
2.
Curylova L, Zambo I, Neradil J, Kyr M, Jurackova N, Pavlova S, et al.
Cell Oncol (Dordr)
. 2024 Dec;
47(6):2317-2334.
PMID: 39630408
Purpose: Pediatric sarcomas are bone and soft tissue tumors that often exhibit high metastatic potential and refractory stem-like phenotypes, resulting in poor outcomes. Aggressive sarcomas frequently harbor a disrupted p53...
3.
Apostolopoulos V, Bohac P, Marcian P, Zambo I, Pazourek L, Mahdal M, et al.
Ann Surg Oncol
. 2024 Jun;
31(9):6333-6334.
PMID: 38824191
No abstract available.
4.
Apostolopoulos V, Bohac P, Marcian P, Zambo I, Pazourek L, Mahdal M, et al.
Ann Surg Oncol
. 2024 May;
31(9):6282-6290.
PMID: 38743283
Background And Objectives: Curettage is the removal of a tumor from the bone while preserving the surrounding healthy cortical bone, and is associated with higher rates of local recurrence. To...
5.
Borankova K, Krchniakova M, Leck L, Kubistova A, Neradil J, Jansson P, et al.
Cell Death Dis
. 2023 Nov;
14(11):747.
PMID: 37973789
Mitochondria are central for cancer responses to therapy-induced stress signals. Refractory tumors often show attenuated sensitivity to apoptotic signaling, yet clinically relevant molecular actors to target mitochondria-mediated resistance remain elusive....
6.
Krchniakova M, Paukovcekova S, Chlapek P, Neradil J, Skoda J, Veselska R
Front Pharmacol
. 2022 Sep;
13:976955.
PMID: 36160437
Tyrosine kinase inhibitors (TKIs) are frequently used in combined therapy to enhance treatment efficacy and overcome drug resistance. The present study analyzed the effects of three inhibitors, sunitinib, gefitinib, and...
7.
Paukovcekova S, Krchniakova M, Chlapek P, Neradil J, Skoda J, Veselska R
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955683
Anticancer therapy by anthracyclines often leads to the development of multidrug resistance (MDR), with subsequent treatment failure. Thiosemicarbazones have been previously suggested as suitable anthracycline partners due to their ability...
8.
Kameneva P, Melnikova V, Kastriti M, Kurtova A, Kryukov E, Murtazina A, et al.
Nat Commun
. 2022 May;
13(1):2901.
PMID: 35614045
Adrenal glands are the major organs releasing catecholamines and regulating our stress response. The mechanisms balancing generation of adrenergic chromaffin cells and protecting against neuroblastoma tumors are still enigmatic. Here...
9.
Macsek P, Skoda J, Krchniakova M, Neradil J, Veselska R
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008802
Despite constant advances in the field of pediatric oncology, the survival rate of high-risk neuroblastoma patients remains poor. The molecular and genetic features of neuroblastoma, such as amplification and stemness...
10.
Mahdal M, Neradil J, Mudry P, Paukovcekova S, Zambo I, Urban J, et al.
Cancers (Basel)
. 2021 Jul;
13(14).
PMID: 34298757
Giant-cell tumor of bone (GCTB) is an intermediate type of primary bone tumor characterized by locally aggressive growth with metastatic potential. The aim of this study was to identify new...