Jaime L Matta
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Explore the profile of Jaime L Matta including associated specialties, affiliations and a list of published articles.
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16
Citations
301
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Recent Articles
1.
Nunez-Marrero A, Arroyo N, Godoy L, Rahman M, Matta J, Dutil J
Oncotarget
. 2020 Sep;
11(37):3420-3431.
PMID: 32973967
Interleukin-12 (IL-12) is a proinflammatory cytokine that links innate and adaptive immune responses against tumor cells. Single Nucleotide Polymorphisms (SNPs) in IL-12 genes have been associated with cancer risk. However,...
2.
Dutil J, Teer J, Golubeva V, Yoder S, Tong W, Arroyo N, et al.
Sci Rep
. 2019 Nov;
9(1):17769.
PMID: 31780696
Inherited pathogenic variants in genes that confer moderate to high risk of breast cancer may explain up to 50% of familial breast cancer. This study aimed at identifying inherited pathogenic...
3.
Diaz-Zabala H, Ortiz A, Garland L, Jones K, Perez C, Mora E, et al.
Cancers (Basel)
. 2018 Nov;
10(11).
PMID: 30400234
Breast cancer is the most common cause of cancer diagnosis in women and is responsible for considerable mortality among the women of Puerto Rico. However, there are few studies in...
4.
Dutil J, Godoy L, Rivera-Lugo R, Arroyo N, Albino E, Negron L, et al.
Genet Test Mol Biomarkers
. 2018 Jan;
22(2):85-89.
PMID: 29356578
Background: The role of deep intronic variants in hereditary cancer susceptibility has been largely understudied. Previously, the BRCA2 c.6937 + 594T>G variant has been shown to preferentially promote the inclusion...
5.
Encarnacion J, Ortiz C, Vergne R, Vargas W, Coppola D, Matta J
Int J Mol Sci
. 2016 Jun;
17(6).
PMID: 27271599
Nucleotide Excision Repair (NER) is a critical pathway involved in breast cancer (BC). We have previously published that a low DNA repair capacity (DRC) is associated with a higher risk...
6.
Dutil J, Golubeva V, Pacheco-Torres A, Diaz-Zabala H, Matta J, Monteiro A
Breast Cancer Res Treat
. 2015 Nov;
154(3):441-53.
PMID: 26564481
Hereditary cancer predisposition gene testing allows the identification of individuals at high risk of cancer that may benefit from increased surveillance, chemoprevention, and prophylactic surgery. In order to implement clinical...
7.
Matta J, Flores I, Morales L, Monteiro J, Alvarez-Garriga C, Bayona M
Mol Cancer Biol
. 2014 Dec;
1(1).
PMID: 25473592
Introduction: Breast cancer (BC) and endometriosis are important reproductive health diseases for women. Although endometriosis is not a malignant condition, some of its characteristics mimic that of a malignancy. Endometriosis...
8.
Perez-Mayoral J, Pacheco-Torres A, Morales L, Acosta-Rodriguez H, Matta J, Dutil J
Mol Carcinog
. 2013 Jun;
52 Suppl 1:E127-38.
PMID: 23776089
Studies have shown that DNA repair capacity (DRC) is significantly decreased in breast cancer patients, but the molecular causes of inter-individual variation in DRC are unknown. We hypothesized that genetic...
9.
Dutil J, Colon-Colon J, Matta J, Sutphen R, Echenique M
Cancer Genet
. 2012 Jun;
205(5):242-8.
PMID: 22682623
Mutations in the breast cancer 1, early onset (BRCA1) and breast cancer 2 (BRCA2) genes are responsible for the majority of hereditary breast cancers. Knowledge of the incidence and prevalence...
10.
Avena S, Via M, Ziv E, Perez-Stable E, Gignoux C, Dejean C, et al.
PLoS One
. 2012 Apr;
7(4):e34695.
PMID: 22506044
The population of Argentina is the result of the intermixing between several groups, including Indigenous American, European and African populations. Despite the commonly held idea that the population of Argentina...