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Jaime A Riquelme

Explore the profile of Jaime A Riquelme including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1101
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Recent Articles
11.
Mondaca-Ruff D, Quiroga C, Norambuena-Soto I, Riquelme J, San Martin A, Bustamante M, et al.
J Cell Mol Med . 2022 Feb; 26(5):1710-1713. PMID: 35118791
Hypertension is associated with high circulating angiotensin II (Ang II). We have reported that autophagy regulates Ang II-induced vascular smooth muscle cell (VSMC) hypertrophy, but the mechanism mediating this effect...
12.
Diaz-Vesga M, Zuniga-Cuevas U, Ramirez-Reyes A, Herrera-Zelada N, Palomo I, Bravo-Sagua R, et al.
Front Cardiovasc Med . 2021 Dec; 8:770421. PMID: 34869687
Despite important advances in the treatment of myocardial infarction that have significantly reduced mortality, there is still an unmet need to limit the infarct size after reperfusion injury in order...
13.
Herrera-Zelada N, Zuniga-Cuevas U, Ramirez-Reyes A, Lavandero S, Riquelme J
Front Pharmacol . 2021 Feb; 12:636134. PMID: 33603675
Despite considerable improvements in the treatment of myocardial infarction, it is still a highly prevalent disease worldwide. Novel therapeutic strategies to limit infarct size are required to protect myocardial function...
14.
Beikoghli Kalkhoran S, Kriston-Vizi J, Hernandez-Resendiz S, Crespo-Avilan G, Rosdah A, Lees J, et al.
Cardiovasc Res . 2021 Jan; 118(1):282-294. PMID: 33386841
Aims: Genetic and pharmacological inhibition of mitochondrial fission induced by acute myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct size. The clinically used anti-hypertensive and heart failure...
15.
Bejarano J, Rojas A, Ramirez-Sagredo A, Riveros A, Morales-Zavala F, Flores Y, et al.
J Control Release . 2020 Nov; 328:859-872. PMID: 33160006
Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled release of...
16.
Riquelme J, Takov K, Santiago-Fernandez C, Rossello X, Lavandero S, Yellon D, et al.
J Cell Mol Med . 2020 Feb; 24(8):4871-4876. PMID: 32101370
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough understanding of their production and function remains elusive. Endothelial senescence is a key feature of vascular ageing...
17.
Olmedo I, Pino G, Riquelme J, Aranguiz P, Diaz M, Lopez-Crisosto C, et al.
Biochim Biophys Acta Mol Basis Dis . 2020 Jan; 1866(5):165659. PMID: 31891806
Cardiomyocyte loss is the main cause of myocardial dysfunction following an ischemia-reperfusion (IR) injury. Mitochondrial dysfunction and altered mitochondrial network dynamics play central roles in cardiomyocyte death. Proteasome inhibition is...
18.
Parra-Flores P, Riquelme J, Valenzuela-Bustamante P, Leiva-Navarrete S, Vivar R, Cayupi-Vivanco J, et al.
Antioxidants (Basel) . 2019 Dec; 8(12). PMID: 31817022
Acute myocardial infarction is one of the leading causes of death worldwide and thus, an extensively studied disease. Nonetheless, the effects of ischemia/reperfusion injury elicited by oxidative stress on cardiac...
19.
Ocaranza M, Riquelme J, Garcia L, Jalil J, Chiong M, Santos R, et al.
Nat Rev Cardiol . 2019 Aug; 17(2):116-129. PMID: 31427727
The renin-angiotensin system is an important component of the cardiovascular system. Mounting evidence suggests that the metabolic products of angiotensin I and II - initially thought to be biologically inactive...
20.
Mondaca-Ruff D, Riquelme J, Quiroga C, Norambuena-Soto I, Sanhueza-Olivares F, Villar-Fincheira P, et al.
Front Pharmacol . 2019 Feb; 9:1553. PMID: 30804791
Hypertension is a disease associated to increased plasma levels of angiotensin II (Ang II). Ang II can regulate proliferation, migration, ROS production and hypertrophy of vascular smooth muscle cells (VSMCs)....