Jacquetta Trasler
Overview
Explore the profile of Jacquetta Trasler including associated specialties, affiliations and a list of published articles.
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45
Citations
828
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Recent Articles
1.
Martinez Duncker Rebolledo E, Chan D, Christensen K, Reagan A, Howell G, Rozen R, et al.
Mol Hum Reprod
. 2024 Feb;
30(4).
PMID: 38366926
5,10-Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that plays a key role in providing methyl groups for DNA methylation, including during spermatogenesis. A common genetic variant in humans (MTHFR 677C>T) results...
2.
Jones S, De Braga V, Caccese C, Lew J, Elgbeili G, Castellanos-Ryan N, et al.
Front Behav Neurosci
. 2024 Jan;
17:1217846.
PMID: 38239262
Introduction: This study examined (1) whether measures of paternal anxious and depressive symptoms collected prenatally and during a follow-up assessment when the child was in middle childhood, predict child neuroendocrine...
3.
Kimmins S, Anderson R, Barratt C, Behre H, Catford S, De Jonge C, et al.
Nat Rev Urol
. 2023 Oct;
21(2):102-124.
PMID: 37828407
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of knowledge around gamete production and how it is affected by genetics and the environment. A...
4.
Karahan G, Martel J, Rahimi S, Farag M, Matias F, MacFarlane A, et al.
Hum Mol Genet
. 2023 Sep;
33(1):48-63.
PMID: 37740387
Assisted reproductive technologies (ART) account for 1-6% of births in developed countries. While most children conceived are healthy, increases in birth and genomic imprinting defects have been reported; such abnormal...
5.
Ducreux B, Patrat C, Trasler J, Fauque P
Hum Reprod Update
. 2023 Sep;
30(1):26-47.
PMID: 37697674
Background: Millions of children have been born throughout the world thanks to ARTs, the harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the specific...
6.
Rahimi S, Shao X, Chan D, Martel J, Berard A, Fraser W, et al.
Clin Epigenetics
. 2023 May;
15(1):82.
PMID: 37170172
Background: Children conceived through assisted reproduction are at an increased risk for growth and genomic imprinting disorders, often linked to DNA methylation defects. It has been suggested that assisted reproductive...
7.
Romero J, Sorin M, Dankner M, Whittaker H, Rose A, Trasler J, et al.
Clin Invest Med
. 2023 Mar;
46(1):E4-14.
PMID: 36966388
Purpose: Women have traditionally been underrepresented in MD and MD-PhD training programs. Here, we describe the changing demographics of an MD-PhD Program over three distinct time intervals. Methods: We designed...
8.
Ihirwe R, Martel J, Rahimi S, Trasler J
FASEB J
. 2022 Dec;
37(1):e22677.
PMID: 36515682
Epigenetic defects induced by assisted reproductive technologies (ART) have been suggested as a potential mechanism contributing to suboptimal placentation. Here, we hypothesize that ART perturbs DNA methylation (DNAme) and gene...
9.
Gorgui J, Sheehy O, Trasler J, Berard A
Front Pharmacol
. 2022 Oct;
13:904885.
PMID: 36249815
Over the last decade, the use of medically assisted reproduction (MAR) has steadily increased but controversy remains with regards to its risks. We aimed to quantify the risk of being...
10.
Maurice C, Dalvai M, Lambrot R, Deschenes A, Scott-Boyer M, McGraw S, et al.
Epigenomes
. 2021 Dec;
5(2).
PMID: 34968297
Due to the grasshopper effect, the Arctic food chain in Canada is contaminated with persistent organic pollutants (POPs) of industrial origin, including polychlorinated biphenyls and organochlorine pesticides. Exposure to POPs...