Jacqueline Blundell
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Explore the profile of Jacqueline Blundell including associated specialties, affiliations and a list of published articles.
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43
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1740
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Recent Articles
1.
Barron J, Dawson L, Carew S, Grace M, Senior K, Ryan K, et al.
Neurobiol Dis
. 2025 Jan;
206:106810.
PMID: 39855476
The consequences of non-pathogenic huntingtin (HTT) reduction in the mature brain are of substantial importance as clinical trials for numerous HTT-lowering therapies are underway; many of which are non-selective in...
2.
Richardson B, Clarke C, Blundell J, Bambico F
Eur J Neurosci
. 2024 Feb;
59(9):2403-2415.
PMID: 38385841
Schizophrenia is a psychotic disorder with an increasing prevalence and incidence over the last two decades. The condition presents with a diverse array of positive, negative, and cognitive impairments. Conventional...
3.
MacCallum P, Cooze J, Ward J, Moore K, Blundell J
Behav Brain Res
. 2024 Jan;
461:114855.
PMID: 38185381
The mechanistic target of rapamycin (mTOR) kinase is known to mediate the formation and persistence of aversive memories. Rapamycin, an mTOR inhibitor, administered around the time of reactivation blocks retrieval-induced...
4.
Wiseman M, Hinks M, Hallett D, Blundell J, Sweeney E, Thorpe C, et al.
J Psychiatr Res
. 2023 Nov;
168:213-220.
PMID: 37918034
Females are twice as likely as males to receive a diagnosis of post-traumatic stress disorder (PTSD). One hypothesis for this sex disparity is that ovarian hormones, including estrogen and progesterone,...
5.
George H, Mercer G, Stapleton D, Dawson L, MacCallum P, Spring S, et al.
Brain Behav
. 2022 Oct;
12(11):e2801.
PMID: 36259950
Introduction: Endothelial nitric oxide synthase (eNOS) produces nitric oxide, which is essential for a variety of physiological functions in the brain. Previous work has demonstrated the detrimental effects of eNOS...
6.
Fillier T, Shah S, Doody K, Pham T, Aubry I, Tremblay M, et al.
Sci Rep
. 2022 Aug;
12(1):14355.
PMID: 35999262
Communication between gut microbiota and the brain is an enigma. Alterations in the gut microbial community affects enteric metabolite levels, such as short chain fatty acids (SCFAs). SCFAs have been...
7.
Waye S, Dinesh O, Hasan S, Conway J, Raymond R, Nobrega J, et al.
J Psychopharmacol
. 2021 Apr;
35(8):1003-1016.
PMID: 33908307
Background: Antidepressant drugs in adolescent depression are sometimes mired by efficacy issues and paradoxical effects. Transcranial direct current stimulation (tDCS) could represent an alternative. Aims/methods: We tested the antidepressant action...
8.
MacCallum P, Blundell J
Psychopharmacology (Berl)
. 2020 Jul;
237(9):2795-2808.
PMID: 32601986
Rationale: The mechanistic target of rapamycin (mTOR) kinase mediates various long-lasting forms of synaptic and behavioural plasticity. However, there is little information concerning the temporal pattern of mTOR activation and...
9.
Lamont M, McCallum P, Head N, Blundell J, Weber J
Psychopharmacology (Berl)
. 2020 Jan;
237(5):1305-1315.
PMID: 31984446
Rationale: To demonstrate that repeated episodes of binge drinking during the adolescent period can lead to long-term deficits in motor function and memory in adulthood, and increase proteins in the...
10.
Bhattacharya S, Fontaine A, MacCallum P, Drover J, Blundell J
Front Behav Neurosci
. 2019 Jun;
13:113.
PMID: 31191267
Although most humans will experience some type of traumatic event in their lifetime only a small set of individuals will go on to develop post-traumatic stress disorder (PTSD). Differences in...